Interrupting the Cycle: Association of Parental Stress and Child/Youth Psychotropic Medication Nonadherence.

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-08-01 Epub Date: 2022-10-28 DOI:10.1007/s10578-022-01448-y

Laura Theall, Ajit Ninan, Kim Arbeau, Jessica Mannone, Shannon L Stewart

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Abstract

Efficacy of psychotropic medication depends in large part on successful adherence to prescribed regimens. This study investigated child/youth nonadherence in relation to family dynamics and informal support. The participants were 10,225 children and youth prescribed psychotropic medication and receiving services from 50 Ontario mental health agencies, assessed with the interRAI™ Child and Youth Mental Health (ChYMH) and ChYMH-Developmental Disability (ChYMH-DD) tools. Findings suggest a cycle of parental stress and child/youth medication nonadherence possibly leading to or even perpetuated by worsening psychiatric symptoms. Informal supports do not appear to moderate this cycle. While the present data cannot speak to causes of medication nonadherence in children/youth or where the cycle begins, the results are consistent with the extant literature calling for attention to parental wellbeing to support children/youth for optimal therapeutic benefits. Understanding home dynamics related to nonadherence can assist care planning that engages the family to achieve best possible child/youth outcomes.

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中断循环：父母压力与儿童/青少年不遵从精神药物治疗的关系。

精神药物的疗效在很大程度上取决于能否成功坚持处方疗程。本研究调查了儿童/青少年不坚持服药与家庭动态和非正式支持的关系。研究对象包括 10,225 名开具精神药物处方并接受安大略省 50 家心理健康机构服务的儿童和青少年，他们接受了 interRAI™ 儿童和青少年心理健康（ChYMH）和儿童和青少年心理健康-发育障碍（ChYMH-DD）工具的评估。研究结果表明，父母的压力和儿童/青少年不坚持服药可能会导致甚至延续精神症状恶化的循环。非正式支持似乎并不能缓解这种循环。虽然目前的数据无法说明儿童/青少年不坚持服药的原因或循环的起始点，但其结果与现有文献中呼吁关注父母健康以支持儿童/青少年获得最佳治疗效果的观点是一致的。了解与不坚持服药相关的家庭动态有助于制定护理计划，让家庭参与其中，以尽可能实现儿童/青少年的最佳治疗效果。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.