Pulmonary mixed squamous and glandular papilloma: diagnostic challenges of a rare lesion when the clock is ticking. How to avoid interpretation mistakes.

IF 4.4 Q1 PATHOLOGY PATHOLOGICA Pub Date : 2022-10-01 DOI:10.32074/1591-951X-809
Iteeka Arora, Nandita Gupta, M Angeles Montero, Patrizia Viola
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Abstract

Pulmonary mixed squamous and glandular papillomas (MSCGPs) are rare, benign neoplasms with peculiar clinical and histological features. However, on occasion, they can present certain characteristics that overlap with other neoplasms including carcinomas. Recognising these features is hence important for treatment purposes. Molecular studies can sometimes help in further characterisation, although they should not guide the diagnosis which ultimately relies on morphology.

We report a challenging case of MSCGP with unusual features, received during intraoperative consultation. We highlight the subtle morphological features to help avoid overcalling a benign lesion as malignant.

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肺混合性鳞状和腺状乳头状瘤:一种罕见病变的诊断挑战。如何避免口译错误。
肺混合鳞状和腺状乳头状瘤(MSCGPs)是罕见的良性肿瘤,具有特殊的临床和组织学特征。然而,有时,它们可以表现出与其他肿瘤(包括癌)重叠的某些特征。因此,识别这些特征对于治疗非常重要。分子研究有时可以帮助进一步的特征,尽管它们不应该指导最终依赖于形态学的诊断。我们报告一个具有不寻常特征的MSCGP病例,在术中咨询期间收到。我们强调细微的形态学特征,以帮助避免将良性病变过度称为恶性病变。
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来源期刊
PATHOLOGICA
PATHOLOGICA PATHOLOGY-
CiteScore
5.90
自引率
5.70%
发文量
108
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