[External Quality Control in Immunohematology of National Medical Center's Blood Bank. History and present].

Isabel Castillo-Mercado, Alexis Ignacio Galván-Bobadilla, Ruth Bonilla-Zavala, Elizabeth González-Moreno, José Alberto Sánchez-Cañas, Rita Villegas-Martínez, Fátima Martha Castillo-Albarrán, Gamaliel Benítez-Arvizu
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Abstract

For the proper functioning of the Immunohematology Area, an External Quality Control was established since 1973 through a program that evaluates the performance of the laboratories of the Blood Bank and transfusion services that carry out immunohematology tests. This program consists of sending panel cells to participating blood banks or services, which are phenotyped erythrocyte samples previously studied as problem cases but whose results are unknown by the participating laboratories. The processes in which the program is of most importance are determination of the ABO group, determination of Rh, performance of the direct and indirect Coombs test, and pre-transfusion compatibility tests. It was carried out an observational and retrospective study of the results obtained in the 2020 period from 104 units participating in the Immunohematology Quality Control Program of the National Medical Center's Blood Bank. A panel of cells was sent for external quality control of immunohematology every 45 days, resulting in 9 panels for each unit in the studied period. Compliance with the program was observed in the general result (79.6%), i.e., there was a decrease in the participation of the registered units. Of a maximum score of 100% to be obtained, it was observed a general result of 95.3% compliance of the participating units. The results obtained confirm the good general training of the immunohematology laboratories of the participating units. Yet, as in any external control program, it becomes clear that obtaining an erroneous result is a risk that can occur in any laboratory.

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[国家医学中心血库免疫血液学外部质量控制。历史与现状]。
为了免疫血液学领域的正常运作,自1973年以来,通过一项评估血库实验室和进行免疫血液学测试的输血服务表现的计划,建立了外部质量控制。该计划包括将面板细胞发送到参与的血库或服务机构,这些细胞是以前作为问题病例研究的表型红细胞样本,但参与实验室未知其结果。该程序最重要的过程是ABO血型的确定、Rh的确定、直接和间接Coombs测试的执行以及输血前兼容性测试。这是对2020年期间104个参与国家医疗中心血库免疫血液学质量控制项目的单位的结果进行的观察性和回顾性研究。每45天发送一组细胞用于免疫血液学的外部质量控制,在研究期间每个单元产生9个细胞组。总体结果(79.6%)符合该计划,即注册单位的参与度有所下降。在最高得分为100%的情况下,观察到参与单位的总体遵守率为95.3%。所获得的结果证实了参与单位免疫血液学实验室的良好总体培训。然而,正如在任何外部控制程序中一样,很明显,获得错误的结果是任何实验室都可能发生的风险。
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