Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA.

Health data science Pub Date : 2021-10-28 eCollection Date: 2021-01-01 DOI:10.34133/2021/9798302
Raj Dandekar, Emma Wang, George Barbastathis, Chris Rackauckas
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Abstract

In the wake of the rapid surge in the COVID-19-infected cases seen in Southern and West-Central USA in the period of June-July 2020, there is an urgent need to develop robust, data-driven models to quantify the effect which early reopening had on the infected case count increase. In particular, it is imperative to address the question: How many infected cases could have been prevented, had the worst affected states not reopened early? To address this question, we have developed a novel COVID-19 model by augmenting the classical SIR epidemiological model with a neural network module. The model decomposes the contribution of quarantine strength to the infection time series, allowing us to quantify the role of quarantine control and the associated reopening policies in the US states which showed a major surge in infections. We show that the upsurge in the infected cases seen in these states is strongly corelated with a drop in the quarantine/lockdown strength diagnosed by our model. Further, our results demonstrate that in the event of a stricter lockdown without early reopening, the number of active infected cases recorded on 14 July could have been reduced by more than 40% in all states considered, with the actual number of infections reduced being more than 100,000 for the states of Florida and Texas. As we continue our fight against COVID-19, our proposed model can be used as a valuable asset to simulate the effect of several reopening strategies on the infected count evolution, for any region under consideration.

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推迟重新开放对控制美国南部和中西部COVID-19激增的影响。
在2020年6月至7月期间,美国南部和中西部地区的covid -19感染病例迅速激增,迫切需要开发强大的数据驱动模型,以量化提前重新开放对感染病例数增加的影响。特别是,必须解决这样一个问题:如果受影响最严重的国家没有尽早重新开放,本可以预防多少感染病例?为了解决这一问题,我们在经典SIR流行病学模型的基础上增加了一个神经网络模块,建立了一个新的COVID-19模型。该模型分解了检疫强度对感染时间序列的贡献,使我们能够量化检疫控制的作用以及美国各州相关的重新开放政策,这些政策显示出感染的大幅增加。我们发现,这些州感染病例的激增与我们的模型诊断出的隔离/封锁强度的下降密切相关。此外,我们的研究结果表明,如果采取更严格的封锁措施,而不提前重新开放,在所有考虑的州,7月14日记录的活跃感染病例数量可能会减少40%以上,佛罗里达州和德克萨斯州的实际感染人数减少了10万以上。随着我们继续抗击COVID-19,我们提出的模型可以作为一种宝贵的资产,用于模拟几种重新开放策略对任何考虑中的地区感染数量演变的影响。
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