Treatment Analysis of Patients Followed up With Postherpetic Neuralgia in Nothern Cyprus.

Dua Cebeci, Seide Karasel
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Abstract

Background: Postherpetic neuralgia (PHN) is a frequent complication of herpes zoster (HZ). Treatment of this chronic pain syndrome and results are often not clear. Tricyclic antidepressants, gabapentinoids and potent opioids are first-line treatments and are highly effective, but their use is limited due to adverse effects that may occur in elderly patients with significant medical comorbidities or interaction due to multiple drug use. There are no head-to-head comparisons of non medical treatments. Dry needling appears comparable to conventional physical therapy for treating PHN.

Objective: Our aim is to determine the incidence of PHN in our population and to compare the treatments in patients with postherpetic neuralgia.

Methods: A search for HZ and PHN was conducted in a general practice research database, comprising 2 general practices (dermatologist and physiatrist) and representing 5600 people. We analyzed a retrospective 37 case with PNH of 170 herpes zoster patient admmited to the dermatology and physical therapy and rehabilitation outpatient clinic between October 2018 and October 2020. Dry needling and physical therapy methods applied in addition to medical treatment in PHN treatment were compared.

Results: In patients with postherpetic neuralgia, both dry needling therapy group and physical therapy group LANSS scores decreased significantly in the first week and in the third week compared to baseline. Dry needling therapy group has also similar results in VAS scores in the first and third week. But in physical therapy group, the VAS score did not show a significant decrease in the first week compared to the baseline, but it decreased significantly in the third week.

Conclusion: PHN is a complex, difficult to treat and severe neuropathic pain that affects patients' daily function and quality of life. Various agents and methods are available to relieve the symptoms of PHN. This study shows as both physical therapy and dry needling therapy are effective treatment for postherpetic nevralgia..

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北塞浦路斯带状疱疹后神经痛患者随访治疗分析。
背景:带状疱疹后带状神经痛(PHN)是带状疱疹的常见并发症。这种慢性疼痛综合征的治疗方法和结果往往不清楚。三环抗抑郁药、加巴喷丁类药物和强效阿片类药物是非常有效的一线治疗方法,但由于有严重合并症的老年患者可能出现不良反应或多种药物使用导致的相互作用,它们的使用受到限制。非医学治疗没有正面比较。干针治疗PHN似乎与传统物理疗法相当。目的:我们的目的是确定人群中PHN的发病率,并比较带状疱疹后神经痛患者的治疗方法。方法:在一个全科医生研究数据库中搜索HZ和PHN,该数据库包括2个全科医生(皮肤科医生和物理医生),代表5600人。我们对2018年10月至2020年10月在皮肤科和物理治疗康复门诊就诊的170例带状疱疹患者中37例PNH进行回顾性分析。比较干针法和物理疗法在药物治疗基础上治疗PHN的效果。结果:在带状疱疹后神经痛患者中,干针治疗组和物理治疗组的LANSS评分在第一周和第三周与基线相比均显著降低。干针治疗组在第1周和第3周VAS评分也有相似的结果。而在物理治疗组,VAS评分在第一周与基线相比没有明显下降,但在第三周明显下降。结论:PHN是一种复杂、难治、严重的神经性疼痛,影响患者的日常功能和生活质量。有多种药物和方法可用于缓解PHN的症状。本研究表明,物理疗法和干针疗法都是治疗带状疱疹后神经痛的有效方法。
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