Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis.

IF 1.4 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Acta Stomatologica Croatica Pub Date : 2022-06-01 DOI:10.15644/asc56/2/9
André Luca Araujo de Sousa, Wanderson Carvalho de Almeida, Jean de Pinho Mendes, Victor Angelo Martins Montalli, Antonione Santos Bezerra Pinto
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Abstract

The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign of bone remodeling and expansion. Therefore, as any early diagnosis minimizes risks and improves the prognosis of treatment for the patient, the aim of this study was, based on a clinical case report, to corroborate the use of histopathological analysis associated with immunohistochemistry. Thus, we conclude that the immunohistochemical exam is of great importance for a better complementation of the MNTI diagnosis process. In addition, it can reveal signs of possible aggressive growth.

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婴儿期黑色素神经外胚层肿瘤:免疫组织化学分析的应用。
婴儿期黑色素神经外胚层肿瘤(MNTI)是一种无症状的色素肿瘤,其特征是快速和局部侵袭性生长,并伴有罕见的组织形成。在诊断过程中,影像学检查可以提示提示恶性肿瘤的局部破坏,是骨重塑和扩张的迹象。因此,由于任何早期诊断都可以最大限度地降低风险并改善患者的治疗预后,因此本研究的目的是基于临床病例报告,证实与免疫组织化学相关的组织病理学分析的使用。因此,我们认为免疫组织化学检查对于更好地补充MNTI诊断过程具有重要意义。此外,它还能显示出可能出现的激进增长迹象。
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来源期刊
Acta Stomatologica Croatica
Acta Stomatologica Croatica DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
2.40
自引率
28.60%
发文量
32
审稿时长
12 weeks
期刊介绍: The Acta Stomatologica Croatica (ASCRO) is a leading scientific non-profit journal in the field of dental, oral and cranio-facial sciences during the past 44 years in Croatia. ASCRO publishes original scientific and clinical papers, preliminary communications, case reports, book reviews, letters to the editor and news. Review articles are published by invitation from the Editor-in-Chief by acclaimed professionals in distinct fields of dental medicine. All manuscripts are subjected to peer review process.
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