[Reproductive and developmental toxicity of organotin compounds].

Q4 Medicine Bulletin of National Institute of Health Sciences Pub Date : 2007-01-01
Makoto Ema
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Abstract

Organotin compounds are chemicals widely used in agriculture and industry. Widespread use of organotins has caused increasing amounts to be released into the environment. Organotins show many aspects of toxicity, such as immunotoxicity, neurotoxicity, and reproductive/developmental toxicity. However, the reproductive and developmental toxicity of organotins is not well understood. The findings of the studies on reproductive and developmental effects of organotin compounds in mammals were summarized in this review.

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[有机锡化合物的生殖和发育毒性]。
有机锡化合物是广泛用于农业和工业的化学品。有机锡的广泛使用导致越来越多的有机锡被释放到环境中。有机锡具有多方面的毒性,如免疫毒性、神经毒性和生殖/发育毒性。然而,有机素的生殖和发育毒性尚不清楚。本文就有机锡化合物对哺乳动物生殖发育影响的研究进展进行综述。
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