A scientific review of middle meatal packing/stents.

Erik Kent Weitzel, Peter-John Wormald
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引用次数: 94

Abstract

Background: Nasal packing usually is placed after endoscopic sinus surgery (ESS) to control hemorrhage, but also may be used to prevent adhesions from forming and promote faster healing of damaged mucosa.

Methods: A literature review was performed to identify all forms of scientifically evaluated absorbable packing for ESS. Only English studies identifiable within the PubMed database were included. Studies were categorized by level of evidence and evaluated for methodological errors.

Results: Thirty-eight studies met the inclusion criteria. There was a diverse range of article evidence and quality.

Conclusion: The most effective hemostatic agent currently available is FloSeal; however, this product causes an increase in adhesion formation. For the purpose of preventing adhesions, resorbable packs appear to have no benefit over either nonresorbables or no packing. If the middle turbinate is unstable at the conclusion of surgery, suturing it to the septum may reduce adhesions. Although mitomycin C, hyaluronic acid, and retinoic acid all have shown potential in these roles, to date, none have shown to be useful in the post-ESS chronic sinusitis human patient.

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中间金属填充物/支架的科学综述。
背景:鼻填充物通常在内窥镜鼻窦手术(ESS)后放置,以控制出血,但也可用于防止粘连形成,促进受损粘膜更快愈合。方法:进行文献回顾,以确定所有形式的科学评估的可吸收包装的ESS。仅包括PubMed数据库中可识别的英语研究。根据证据水平对研究进行分类,并对方法错误进行评估。结果:38项研究符合纳入标准。文章的证据和质量各不相同。结论:目前最有效的止血药物是FloSeal;然而,这种产品会导致粘连形成的增加。为了防止粘连,可吸收的包装似乎没有任何好处比不可吸收或没有包装。如果手术结束时中鼻甲不稳定,将其缝合到鼻中隔可减少粘连。尽管丝裂霉素C、透明质酸和视黄酸都显示出在这些作用中的潜力,但迄今为止,没有一种显示出在ess后慢性鼻窦炎患者中有用。
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