Recurrence of disease in a patient with Covid-19: Re-activation or re-infection?

IF 0.4 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL National Medical Journal of India Pub Date : 2022-05-01 DOI:10.25259/NMJI-35-3-165
Abhinav Shrivastava, Satyajit Padhiari, Rajnish Singh
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Abstract

Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) was expected to induce a monophasic disease with subsequent immunity. However, case reports have since emerged which have found patients with either re-infection or re-activation of the virus. We describe a 44-year-old man with severe Covid-19-induced pneumonia who had recurrence of the disease after testing Covid-19-negative on three consecutive reverse transcriptase-polymerase chain reaction (RT-PCR) tests. Our patient underlines that caution should be exercised while planning for discharge of a patient irrespective of his previous negative test, especially in vulnerable patients and those who had moderate-to-severe disease requiring the use of immunosuppressive therapy. The fact that such patients could experience a re-activation or re-infection, requires monitoring and vigilance in the management of the pandemic at individual and collective levels.

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Covid-19患者疾病复发:再激活还是再感染?
严重急性呼吸综合征冠状病毒2 (SARSCoV-2)有望诱导单相疾病,随后产生免疫。然而,此后出现了病例报告,发现患者再次感染或重新激活病毒。我们描述了一名44岁的男性,他患有covid -19引起的严重肺炎,在连续三次逆转录聚合酶链反应(RT-PCR)检测中呈covid -19阴性后,疾病复发。我们的患者强调,在计划患者出院时应谨慎行事,无论其既往检测结果为阴性,特别是在易感患者和需要使用免疫抑制治疗的中重度疾病患者中。鉴于此类患者可能再次激活或再次感染,需要在个人和集体层面对大流行的管理进行监测和保持警惕。
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来源期刊
National Medical Journal of India
National Medical Journal of India 医学-医学:内科
CiteScore
0.50
自引率
0.00%
发文量
171
审稿时长
>12 weeks
期刊介绍: The journal will cover technical and clinical studies related to health, ethical and social issues in field of health policy and health provider training through sections on ‘Medicine and society’ and ‘Medical education’.. Articles with clinical interest and implications will be given preference.
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