Evaluation of 3T proton MR spectroscopy in the spinal cord - preliminary results.

IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Polish Journal of Radiology Pub Date : 2022-07-08 eCollection Date: 2022-01-01 DOI:10.5114/pjr.2022.118194
Pawel Wawrzyniak, Anna Hebda, Sylwia Heinze, Barbara Bobek-Billewicz
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Abstract

Purpose: 1H-magnetic resonance spectroscopy (1H-MRS) is a non-invasive technique that provides information on tissue metabolism and biochemistry. Because of technical difficulties, this method is rarely used in spinal cord examination. The main goal of this study was to develop a routine protocol for MRS of intramedullary lesions.

Material and methods: A 1H-MRS protocol was set on a group of healthy volunteers. Forty-eight spectra were acquired in total. Thirty of them were acquired in cervical spinal cord, and the remaining 18 spectra were acquired in the thoracic spinal cord.

Results: In 1H-MRS of the spinal cord one of the most important problems is small voxel size. Mean voxel size in this study was 7 × 9 × 29 mm, which is much smaller than in brain examinations. Finally, almost 60% of spectra were of acceptable quality in volunteer examinations, which enabled the subsequent examinations.

Conclusions: Challenges of spinal cord spectroscopy were discussed, and the ability of providing additional diagnostic information was proven.

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脊髓3T质子磁共振光谱的评价-初步结果。
目的:磁共振波谱(1H-MRS)是一种提供组织代谢和生物化学信息的无创技术。由于技术上的困难,这种方法很少用于脊髓检查。本研究的主要目的是制定髓内病变的MRS常规方案。材料与方法:对健康志愿者进行1H-MRS实验。共获得48个光谱。其中30个谱分布于颈脊髓,其余18个谱分布于胸脊髓。结果:在脊髓1H-MRS中,最重要的问题之一是体素小。本研究的平均体素大小为7 × 9 × 29 mm,远小于脑部检查。最后,近60%的光谱在自愿检查中质量可接受,这使得后续检查成为可能。结论:讨论了脊髓光谱学的挑战,并证明了提供额外诊断信息的能力。
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Polish Journal of Radiology
Polish Journal of Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
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