The Profile of Articles on AXIN2 Mutations, Oligodontia, and Ethical Statements in Dental Research.

IF 1.7 4区哲学 Q2 ETHICS Journal of Empirical Research on Human Research Ethics Pub Date : 2022-10-01 Epub Date: 2022-07-25 DOI:10.1177/15562646221116801

R Constance Wiener

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Abstract

Purpose: Editors often require ethical statements in research publications. This is particularly important with genetic data where discrimination may occur upon data disclosures. The purpose of this research is to determine if there was a positive trend of publishing ethical statements in dental genetic research. The study is limited to AXIN2 mutations which may be associated with oligodontia and cancer.

Methods: A MEDLINE search of 2011-2021 articles concerning AXIN2, oligodontia, and ethical statements was conducted. Reviews, nonhuman subject research, abstracts, and articles not written nor translated into English were excluded.

Results: Forty-four studies were found; 10 excluded. There were 25 (75.8%) with ethical statements, and 25 (75.8%) with participant consent statements. There was no significant difference by year in ethical statements over the ten years (p = 0.094).

Conclusion: There is a need to encourage more ethical statements in publications especially for genetically sensitive topics to reassure readers of ethical practices.

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关于AXIN2突变、少齿症和牙科研究伦理声明的文章简介。

目的:编辑通常要求在研究出版物中发表伦理声明。这对于基因数据尤其重要，因为数据披露可能会产生歧视。本研究的目的是确定是否有一个积极的趋势，发表伦理声明在牙科遗传研究。这项研究仅限于可能与少齿症和癌症相关的AXIN2突变。方法:在MEDLINE检索2011-2021年有关AXIN2、少齿症和伦理声明的文章。综述、非人类受试者研究、摘要和未写或未翻译成英文的文章被排除在外。结果:共发现44项研究;10排除在外。25份(75.8%)有伦理声明，25份(75.8%)有参与者同意声明。十年间不同年份的伦理陈述差异无统计学意义(p = 0.094)。结论:有必要在出版物中鼓励更多的伦理声明，特别是对于基因敏感的话题，以使读者对伦理实践放心。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Empirical Research on Human Research Ethics 医学-医学：伦理

CiteScore

3.50

自引率

7.70%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Empirical Research on Human Research Ethics (JERHRE) is the only journal in the field of human research ethics dedicated exclusively to empirical research. Empirical knowledge translates ethical principles into procedures appropriate to specific cultures, contexts, and research topics. The journal''s distinguished editorial and advisory board brings a range of expertise and international perspective to provide high-quality double-blind peer-reviewed original articles.