Metabolic bariatric surgery in the treatment of obesity complicated with hypertension: mechanistic insight.

IF 2 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Discovery medicine Pub Date : 2022-05-01
Jian Wang, Xiaotao Wang, Xinzhe Zhai, Yisen Hou, Jianli Han
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Abstract

The increase of dietary fat energy supply ratio has led to a gradual increase in obesity, and the risk of hypertension in patients with obesity is much higher than that in the normal population. Weight loss has become a popular method to control obesity and hypertension. Metabolic bariatric surgery (MBS), which is also called weight loss surgery, can have significant effects on the weight and body metabolism of the patients. Recent studies have shown that the blood pressure of obese patients with hypertension is significantly improved after MBS. Therefore, in this review we will briefly describe the relationship between obesity and hypertension, summarize the effects of MBS on hypertension, and then focus on the mechanisms by which MBS achieves satisfactory efficacy to treat hypertension.

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代谢减肥手术治疗肥胖合并高血压:机制洞察。
膳食脂肪能量供给比的增加导致肥胖人群逐渐增多,肥胖患者高血压的发生风险远高于正常人群。减肥已经成为控制肥胖和高血压的流行方法。代谢减肥手术(Metabolic ariariric surgery, MBS),又称减肥手术,可以对患者的体重和身体代谢产生显著的影响。最近的研究表明,肥胖高血压患者在MBS后血压有明显改善。因此,本文将简要介绍肥胖与高血压的关系,总结MBS对高血压的作用,并重点探讨MBS治疗高血压的作用机制。
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来源期刊
Discovery medicine
Discovery medicine MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
5.40
自引率
0.00%
发文量
80
审稿时长
6-12 weeks
期刊介绍: Discovery Medicine publishes novel, provocative ideas and research findings that challenge conventional notions about disease mechanisms, diagnosis, treatment, or any of the life sciences subjects. It publishes cutting-edge, reliable, and authoritative information in all branches of life sciences but primarily in the following areas: Novel therapies and diagnostics (approved or experimental); innovative ideas, research technologies, and translational research that will give rise to the next generation of new drugs and therapies; breakthrough understanding of mechanism of disease, biology, and physiology; and commercialization of biomedical discoveries pertaining to the development of new drugs, therapies, medical devices, and research technology.
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