Mohammad Reza Ghaffary, Ali Talei, Maryam Moradian, Shamsi Ghaffari
{"title":"The effect of fasting on spirometry indices and respiratory symptoms in asthmatic patients.","authors":"Mohammad Reza Ghaffary, Ali Talei, Maryam Moradian, Shamsi Ghaffari","doi":"10.34172/jcvtr.2022.21","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Ramadan can alter the course of diseases by changing nutrition patterns, sleep habits, and medication-taking schedules. There are some concerns that patients with asthma may be affected by these alterations during Ramadan and experience deterioration of their symptoms. This study aimed to investigate the effect of fasting in Ramadan on the severity of the disease and spirometric parameters in patients with asthma. <b><i>Methods:</i></b> An overall 120 patients with moderate to severe asthma were investigated during Ramadan and categorized into two groups of fasting (60 cases) and non-fasting (60 cases) groups. Patients underwent spirometry before and after Ramadan and asthma control status was also assessed. The parameters measured in spirometry were compared in each group before and after Ramadan and also between the two groups. <b><i>Results:</i></b> Spirometric measurements including forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF), and FEV1/FVC were not significantly different before and after Ramadan in both groups of fasting and non-fasting patients. Furthermore, there was no significant difference between the two groups in terms of these spirometric parameters changes from baseline. Nevertheless, FEV1 change in the fasting group was significantly higher than that in the non-fasting group (1.46±5.37 vs. -0.13±3.08, respectively; <i>P</i>=0.040). <b><i>Conclusion:</i></b> The results of this study demonstrated that fasting has no significant effect on the severity of asthma and spirometric findings in patients with moderate to severe asthma. Therefore, fasting during Ramadan can be considered safe for patients with asthma.</p>","PeriodicalId":15207,"journal":{"name":"Journal of Cardiovascular and Thoracic Research","volume":"14 2","pages":"116-121"},"PeriodicalIF":1.2000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339731/pdf/","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cardiovascular and Thoracic Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/jcvtr.2022.21","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/6/28 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 1
Abstract
Introduction: Ramadan can alter the course of diseases by changing nutrition patterns, sleep habits, and medication-taking schedules. There are some concerns that patients with asthma may be affected by these alterations during Ramadan and experience deterioration of their symptoms. This study aimed to investigate the effect of fasting in Ramadan on the severity of the disease and spirometric parameters in patients with asthma. Methods: An overall 120 patients with moderate to severe asthma were investigated during Ramadan and categorized into two groups of fasting (60 cases) and non-fasting (60 cases) groups. Patients underwent spirometry before and after Ramadan and asthma control status was also assessed. The parameters measured in spirometry were compared in each group before and after Ramadan and also between the two groups. Results: Spirometric measurements including forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF), and FEV1/FVC were not significantly different before and after Ramadan in both groups of fasting and non-fasting patients. Furthermore, there was no significant difference between the two groups in terms of these spirometric parameters changes from baseline. Nevertheless, FEV1 change in the fasting group was significantly higher than that in the non-fasting group (1.46±5.37 vs. -0.13±3.08, respectively; P=0.040). Conclusion: The results of this study demonstrated that fasting has no significant effect on the severity of asthma and spirometric findings in patients with moderate to severe asthma. Therefore, fasting during Ramadan can be considered safe for patients with asthma.
简介:斋月可以通过改变营养模式、睡眠习惯和服药时间表来改变疾病的进程。有些人担心,哮喘患者可能会在斋月期间受到这些改变的影响,并经历症状恶化。本研究旨在探讨斋月禁食对哮喘患者疾病严重程度和肺活量指标的影响。方法:选取斋月期间中重度哮喘患者120例,分为禁食组(60例)和非禁食组(60例)。患者在斋月前后进行肺活量测定,并评估哮喘控制状况。比较两组患者斋月前后肺活量测定指标。结果:两组禁食和非禁食患者的第一秒用力呼气量(FEV1)、用力肺活量(FVC)、呼气峰流量(PEF)、FEV1/FVC等肺活量测定在斋月前后无显著差异。此外,两组之间在这些肺活量参数从基线变化方面没有显著差异。然而,空腹组的FEV1变化明显高于非空腹组(分别为1.46±5.37 vs -0.13±3.08;P = 0.040)。结论:本研究结果表明,禁食对中重度哮喘患者的哮喘严重程度和肺活量测定结果无显著影响。因此,在斋月期间禁食对哮喘患者来说是安全的。