COVID-19, Influenza, and Other Acute Respiratory Viral Infections: Etiology, Immunopathogenesis, Diagnosis, and Treatment. Part I. COVID-19 and Influenza.

Pub Date : 2022-01-01 Epub Date: 2022-08-01 DOI:10.3103/S0891416822010025
T N Ilyicheva, S V Netesov, V N Gureyev
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引用次数: 1

Abstract

The paper briefly reviews pathogens causing acute respiratory viral infections (ARVIs), including influenza viruses; coronaviruses, including SARS-CoV-2; parainfluenza viruses, adenoviruses, pneumoviruses, and specifically respiratory syncytial virus and metapneumoviruses, enteroviruses, rhinoviruses, and bocaviruses. This review presents modern data on the structure and replication of viruses, epidemiology, and immunopathogenesis of diseases and on diagnostics, preventive vaccination, and antiviral drugs for the treatment of ARVIs. Special attention is paid to the SARS-CoV-2 virus caused COVID-19 pandemic with analyses of similarities and differences between COVID-19 and other ARVIs, first of all, influenza virus. Topical issues regarding ARVI vaccination and the search for new broad-spectrum antiviral drugs are discussed.

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COVID-19、流感和其他急性呼吸道病毒感染:病因、免疫发病机制、诊断和治疗。第一部分:COVID-19和流感。
本文简要综述了引起急性呼吸道病毒感染(ARVIs)的病原体,包括流感病毒;冠状病毒,包括SARS-CoV-2;副流感病毒、腺病毒、肺炎病毒,特别是呼吸道合胞病毒和偏肺病毒、肠病毒、鼻病毒和bocavavirus。本文综述了病毒的结构和复制、流行病学、疾病的免疫发病机制、诊断、预防性疫苗接种和治疗ARVIs的抗病毒药物等方面的最新数据。特别关注SARS-CoV-2病毒引起的COVID-19大流行,分析了COVID-19与其他抗逆转录病毒药物(首先是流感病毒)的异同。讨论了有关ARVI疫苗接种和寻找新的广谱抗病毒药物的热点问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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