Cascading Effects of Conspecific Aggression on Oxidative Status and Telomere Length in Zebra Finches.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2022-09-01 DOI:10.1086/721252
Martin Quque, Charly Ferreira, Sebastian Sosa, Quentin Schull, Sandrine Zahn, François Criscuolo, Josefa Bleu, Vincent A Viblanc
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引用次数: 1

Abstract

Living in social groups may exacerbate interindividual competition for territory, food, and mates, leading to stress and possible health consequences. Unfavorable social contexts have been shown to elevate glucocorticoid levels (often used as biomarkers of individual stress), but the downstream consequences of socially stressful environments are rarely explored. Our study experimentally tests the mechanistic links between social aggression, oxidative stress, and somatic maintenance in captive zebra finches (Taeniopygia guttata). Over 64 d, we measured the effects of aggression (received or emitted) on the individual oxidative status, body condition, and changes in relative telomere length (rTL) of birds living in high- and low-social-density conditions. Using path analyses, we found that birds living at high social density increased their aggressive behavior. Birds receiving the highest number of aggressions exhibited the strongest activation of antioxidant defenses and highest plasmatic levels of reactive oxygen metabolites. In turn, this prevented birds from maintaining or restoring telomere length between the beginning and the end of the experiment. Received aggression also had a direct negative effect on changes in rTL, unrelated to oxidative stress. In contrast, emitted aggression had no significant effect on individual oxidative stress or changes in rTL. Body condition did not appear to affect the physiological response to aggression or oxidative stress. At low density, we found trends that were similar to those at high density but nonsignificant. Our study sheds light on the causal chain linking the social environment and aggressive behavior to individual oxidative stress and telomere length. The long-term consequences of socially induced stress on fitness remain to be characterized.

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同种攻击对斑胸草雀氧化状态和端粒长度的级联效应。
生活在社会群体中可能会加剧个体间对领土、食物和配偶的竞争,导致压力和可能的健康后果。不利的社会环境已被证明会提高糖皮质激素水平(通常用作个体压力的生物标志物),但社会压力环境的下游后果很少被探索。本研究通过实验验证了圈养斑胸草雀(Taeniopygia guttata)社会攻击、氧化应激和躯体维持之间的机制联系。在64 d内,我们测量了攻击(接收或发射)对生活在高和低社会密度条件下的鸟类个体氧化状态、身体状况和相对端粒长度(rTL)变化的影响。通过通径分析,我们发现高社会密度的鸟类的攻击行为增加。受到攻击次数最多的鸟类表现出最强的抗氧化防御激活和最高的血浆活性氧代谢物水平。反过来,这阻止了鸟类在实验开始和结束之间维持或恢复端粒长度。受到性攻击对rTL的变化也有直接的负面影响,与氧化应激无关。相比之下,发射攻击对个体氧化应激和rTL的变化没有显著影响。身体状况似乎不影响对攻击或氧化应激的生理反应。在低密度时,我们发现趋势与高密度时相似,但不显著。我们的研究揭示了社会环境和攻击行为与个体氧化应激和端粒长度之间的因果链。社会诱导的压力对健康的长期影响仍有待研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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