Progress in the Study of Optical Probes for the Detection of Formaldehyde.

IF 4.2 2区 化学 Q1 CHEMISTRY, ANALYTICAL Critical reviews in analytical chemistry Pub Date : 2024-08-01 Epub Date: 2022-08-08 DOI:10.1080/10408347.2022.2107870
Xuexuan Xu, Erpei Yang, Yanyan Chen
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Abstract

Formaldehyde, one of the simplest reactive carbonyl substances, is involved in many physiological and pathological processes in living organisms. There is a large amount of data showing that abnormal elevation of formaldehyde is associated with a variety of diseases in the body, such as neurodegenerative diseases, Alzheimer's disease, cardiovascular diseases and cancer, and is also a representative carcinogen, so monitoring formaldehyde is of great importance for disease diagnosis and treatment. In this review, In this paper, we summarize and classify the last ten years of probes for the detection of formaldehyde according to different reaction mechanisms and discuss the structures and applications of the probes. Finally, we briefly describe the challenges and possible solutions in this field. We believe that more new probes provide powerful tools to study the function of formaldehyde in living systems.

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用于检测甲醛的光学探针的研究进展。
甲醛是最简单的活性羰基物质之一,参与生物体的许多生理和病理过程。大量数据表明,甲醛的异常升高与机体的多种疾病有关,如神经退行性疾病、老年痴呆症、心血管疾病和癌症等,也是一种代表性的致癌物质,因此监测甲醛对疾病的诊断和治疗具有重要意义。在这篇综述中,我们根据不同的反应机理对近 10 年来用于检测甲醛的探针进行了总结和分类,并讨论了探针的结构和应用。最后,我们简要介绍了该领域面临的挑战和可能的解决方案。我们相信,更多的新探针将为研究甲醛在生命系统中的功能提供强有力的工具。
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来源期刊
CiteScore
12.00
自引率
4.00%
发文量
137
审稿时长
6 months
期刊介绍: Critical Reviews in Analytical Chemistry continues to be a dependable resource for both the expert and the student by providing in-depth, scholarly, insightful reviews of important topics within the discipline of analytical chemistry and related measurement sciences. The journal exclusively publishes review articles that illuminate the underlying science, that evaluate the field''s status by putting recent developments into proper perspective and context, and that speculate on possible future developments. A limited number of articles are of a "tutorial" format written by experts for scientists seeking introduction or clarification in a new area. This journal serves as a forum for linking various underlying components in broad and interdisciplinary means, while maintaining balance between applied and fundamental research. Topics we are interested in receiving reviews on are the following: · chemical analysis; · instrumentation; · chemometrics; · analytical biochemistry; · medicinal analysis; · forensics; · environmental sciences; · applied physics; · and material science.
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