Estimating Worldwide Impact of Low Physical Activity on Risk of Developing Ischemic Heart Disease-Related Disability: An Updated Search in the 2019 Global Health Data Exchange (GHDx).

Giuseppe Lippi, Fabian Sanchis-Gomar, Camilla Mattiuzzi, Carl J Lavie
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Abstract

We provide here updated analysis of the impact of physical inactivity on risk of developing ischemic heart disease (IHD)-related disability along with the latest 10-year progression. We collected data through an electronic search in the 2019 Global Health Data Exchange (GHDx) database using the keywords "low physical activity", complemented with the additional epidemiologic variables "disability-adjusted life years" (DALYs; number); "ischemic heart disease"; "socio-demographic index" (SDI); "age"; "sex" and "year", for calculating volume of DALYs lost due to physical activity (PA)-related disability after IHD (LPA-IHD impairment). Based on this search, the overall LPA-IHD impairment was estimated at 7.6 million DALYs in 2019 (3.9 and 3.7 million DALYs in males and females, respectively), thus representing nearly 50% of all PA-related disabilities. The highest impact of LPA-IHD impairment was observed in middle SDI countries, being the lowest in low SDI countries. The LPA-IHD DALYs increased by 17.5% in both sexes during the past 10 years (19.2% in males, and 15.8% in females, respectively), though this trend was dissimilar among different SDI areas, especially during the past two years. In high and high-middle SDI countries, the LPA-IHD grew during the past 2 years, whilst the trend remained stable or declined in other regions. In conclusion, LPA-IHD impairment remains substantial worldwide, leading the way to reinforce current policies aimed at increasing PA volume in the population.

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估计低体力活动对缺血性心脏病相关残疾风险的全球影响:2019年全球健康数据交换(GHDx)中的最新搜索
我们在此提供了最新的分析,分析了缺乏运动对缺血性心脏病(IHD)相关残疾风险的影响,以及最近10年的进展。我们通过2019年全球健康数据交换(GHDx)数据库中的电子搜索收集数据,使用关键词“低体力活动”,并辅以额外的流行病学变量“残疾调整生命年”(DALYs;数);“缺血性心脏病”;“社会人口指数”;“年龄”;“性别”和“年份”,用于计算IHD (LPA-IHD损伤)后因体力活动(PA)相关残疾而损失的伤残调整生活年数。根据这项研究,2019年LPA-IHD的总体损害估计为760万DALYs(男性和女性分别为390万和370万DALYs),因此占所有pa相关残疾的近50%。LPA-IHD损害在中等SDI国家的影响最大,在低SDI国家的影响最小。LPA-IHD DALYs在过去10年中男女均增加了17.5%(男性分别为19.2%,女性分别为15.8%),尽管这一趋势在不同的SDI地区有所不同,特别是在过去两年。在高和中高SDI国家,LPA-IHD在过去2年中有所增长,而其他区域的趋势保持稳定或下降。总之,LPA-IHD缺陷在世界范围内仍然很严重,导致加强旨在增加人口中PA量的现行政策。
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