Cognitive-Motor Interference and Cortical Activation While Walking in Individuals With Multiple Sclerosis.

IF 0.9 4区 医学 Q4 NEUROSCIENCES Motor Control Pub Date : 2022-08-13 Print Date: 2022-10-01 DOI:10.1123/mc.2021-0051
Michael VanNostrand, Brittany Belanger, Gabriel Purin, Susan L Kasser, Michael Cannizzaro
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Abstract

The present study expands on current understanding of dual-task cognitive-motor interference, by including cortical activation measures to both traditional and ecologically valid dual-task paradigms. Fifteen individuals with multiple sclerosis and 14 control participants underwent mobility testing while wearing functional near-infrared spectroscopy. In the absence of increased prefrontal cortical activation, subjects with multiple sclerosis performed significantly worse on measures of cognition under both single- and dual-task conditions. These findings suggest that persons with multiple sclerosis may be unable to allocate additional cortical resources to cognition under dual-task conditions, leading to significant cognitive-motor interference and decrements in performance. This study is the first to investigate cortical activation across several commonly used and ecologically valid dual-task assessments.

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多发性硬化症患者行走时的认知运动干扰和皮质激活。
本研究扩展了目前对双任务认知运动干扰的理解,包括对传统和生态有效的双任务范式的皮层激活测量。15名多发性硬化症患者和14名对照组参与者在佩戴功能性近红外光谱仪的同时进行了活动能力测试。在前额皮质没有增加激活的情况下,多发性硬化症受试者在单任务和双任务条件下的认知测试中表现明显更差。这些发现表明,患有多发性硬化症的人可能无法在双重任务条件下分配额外的皮质资源来认知,导致显著的认知运动干扰和表现下降。这项研究首次调查了几种常用和生态有效的双任务评估中的皮层激活。
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来源期刊
Motor Control
Motor Control 医学-神经科学
CiteScore
1.80
自引率
9.10%
发文量
48
审稿时长
>12 weeks
期刊介绍: Motor Control (MC), a peer-reviewed journal, provides a multidisciplinary examination of human movement across the lifespan. To keep you abreast of current developments in the field of motor control, it offers timely coverage of important topics, including issues related to motor disorders. This international journal publishes many types of research papers, from clinical experimental to modeling and theoretical studies. These papers come from such varied disciplines as biomechanics, kinesiology, neurophysiology, neuroscience, psychology, physical medicine, and rehabilitation. Motor Control, the official journal of the International Society of Motor Control, is designed to provide a multidisciplinary forum for the exchange of scientific information on the control of human movement across the lifespan, including issues related to motor disorders. Motor Control encourages submission of papers from a variety of disciplines including, but not limited to, biomechanics, kinesiology, neurophysiology, neuroscience, psychology, physical medicine, and rehabilitation. This peer-reviewed journal publishes a wide variety of types of research papers including clinical experimental, modeling, and theoretical studies. To be considered for publication, papers should clearly demonstrate a contribution to the understanding of control of movement. In addition to publishing research papers, Motor Control publishes review articles, quick communications, commentaries, target articles, and book reviews. When warranted, an entire issue may be devoted to a specific topic within the area of motor control.
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