WITHDRAWN: Bismuth(III) Complexes with Schiff Bases: Synthesis, Characterization, Interaction with Biomolecules, Antioxidant and Antimicrobial Activity

IF 1.9 4区 医学 Q3 CHEMISTRY, MEDICINAL Medicinal Chemistry Pub Date : 2025-01-01 DOI:10.2174/1573406419666221118104019
Maxim Y Gvozdev, Natalia V Loginova, Galina A Ksendzova, Nikolai P Osipovich, Tat'yana V Koval'chuk-Rabchinskaya, Yaroslav V Faletrov, Alina M Khodosovskaya, Anatoly N Evtushenkov
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Abstract

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been withdrawn.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham science disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

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铋(III)与希夫碱的配合物:合成、表征、与生物大分子的相互作用、抗氧化和抗菌活性。
目的和背景:与抗生素不同,金属络合物可以实现一种以上的杀菌作用机制,以对抗多重耐药菌株(主要是由于金属离子),涉及微生物细胞壁中的功能基团和各种酶等目标。潜在的抗菌剂包括 Bi(III)与二苯酚的配合物:本研究旨在合成和研究新型 Bi(III)与希夫碱的配合物,作为潜在的抗菌剂和抗氧化剂:方法:通过元素分析、傅立叶变换红外光谱、紫外可见光谱、1H NMR 光谱、XRD、循环伏安法和电导率测量以及生物学方法对 Bi(III)配合物进行表征:这些配合物的化学式为 Bi(L)2Cl,其配位核心为 BiO2N2Cl,呈金字塔几何形状,其中 Bi(III)阳离子由羟基和偶氮甲基配位。配体以单阴离子形式配位。与配体相比,配合物更亲脂,对测试细菌的生物活性更高。配体及其复合物都具有还原 Fe(III)-Cyt c 的能力,并且还原率相当。所有化合物都具有 DPPH 和 ABTS 自由基清除活性,在 CUPRAC 试验中,它们也是比 Trolox 更有效的还原剂。复合物与 BSA 相互作用的特殊性表明,BSA 的 Cys-34 不是这些复合物的主要结合位点。根据分子对接研究,复合物通过非共价相互作用与 BSA 结合:结论:Bi(III) 与希夫碱的络合在其抗菌和抗氧化活性以及与 BSA 的相互作用中发挥了重要作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medicinal Chemistry
Medicinal Chemistry 医学-医药化学
CiteScore
4.30
自引率
4.30%
发文量
109
审稿时长
12 months
期刊介绍: Aims & Scope Medicinal Chemistry a peer-reviewed journal, aims to cover all the latest outstanding developments in medicinal chemistry and rational drug design. The journal publishes original research, mini-review articles and guest edited thematic issues covering recent research and developments in the field. Articles are published rapidly by taking full advantage of Internet technology for both the submission and peer review of manuscripts. Medicinal Chemistry is an essential journal for all involved in drug design and discovery.
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