Herpes Zoster after mRNA COVID-19 Vaccination: A Case Series.

Q4 Medicine Skinmed Pub Date : 2022-08-31 eCollection Date: 2022-01-01
Alexandra Monastirli, Efstathia Pasmatzi, George Badavanis, Gianna Panagiotopoulou, Assimina Apostolidou, Dionysios Tsambaos
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Abstract

We present seven immunocompetent patients devoid of any comorbidities and risk factors, who developed for the first time in their life varicella-zoster virus (VZV) reactivation shortly after 1st (four patients) and 2nd dose (three patients) of mRNA COVID-19 vaccines.All four patients who exhibited herpes zoster after the 1st dose of vaccine received the 2nd dose without any adverse reactions or complications. Oral treatment prescribed to all patients with valacyclovir (Valtrex 1 mg tds/day) for 5-7 days led to a complete resolution of symptoms, and rashes disappeared within 9-14 days. Presently, All patients have completed a 3-4½-month follow-up without any evidence of complications and/or recurrence of herpes zoster. (SKINmed. 2022;20:284-288).

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mRNA - COVID-19疫苗接种后带状疱疹:一个病例系列
我们报告了7例无任何合并症和危险因素的免疫功能正常的患者,他们在第一次(4例)和第二次(3例)mRNA COVID-19疫苗接种后不久首次出现水痘带状疱疹病毒(VZV)再激活。所有4例在接种第一剂疫苗后出现带状疱疹的患者均接受了第二剂疫苗,没有出现任何不良反应或并发症。所有患者口服valacyclovir (Valtrex 1mg tds/day)治疗5-7天,症状完全缓解,皮疹在9-14天内消失。目前,所有患者都完成了3-4个半月的随访,没有任何并发症和/或带状疱疹复发的证据。(SKINmed。20:284 2022; 288)。
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来源期刊
Skinmed
Skinmed Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
99
期刊介绍: SKINmed is a peer-reviewed bimonthly publication circulated to more than 28,000 dermatologists, allergists, internists, pediatricians, and family practitioners with an interest in dermatology and allergy. SKINmed features articles, original papers, and case studies concerning clinical aspects of dermatology, including dermatopathology, diagnostics, occupational dermatology, malignancy/tumors, cosmetic dermatology, endocrine diseases, infestations, infections, and pharmacotherapy.
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