{"title":"Paper chromatography and chemical structure","authors":"J. Green, S. Marcinkiewicz","doi":"10.1016/0009-5907(63)81008-X","DOIUrl":null,"url":null,"abstract":"<div><p>The effect of tautomerism on <em>R<sub>M</sub></em> has been studied. The general nature of the effect on chromatography is discussed and equations obtained by means of which the existence of tautomerism can be verified chromatographically. If sufficient data are available from the study of archetypal compounds in which each form of the tautomeric group occurs free from other constitutive effects, it is possible, by these equations, to calculate the position of tautomeric equilibrium in a given compound. The procedure is illustrated with reference to the tautomerism of thienol (2-hydroxythiophen), <em>p</em>-nitrosophenol and 4-nitroso-I-naphthol. The procedure followed rests on the adherence of many group and structural Δ<em>R<sub>M</sub></em> parameters to the additivity principle of <span><math><mtext>Martin</mtext></math></span>'s equation.</p></div>","PeriodicalId":78892,"journal":{"name":"Chromatographic reviews","volume":"5 ","pages":"Pages 123-134"},"PeriodicalIF":0.0000,"publicationDate":"1963-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0009-5907(63)81008-X","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chromatographic reviews","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/000959076381008X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
The effect of tautomerism on RM has been studied. The general nature of the effect on chromatography is discussed and equations obtained by means of which the existence of tautomerism can be verified chromatographically. If sufficient data are available from the study of archetypal compounds in which each form of the tautomeric group occurs free from other constitutive effects, it is possible, by these equations, to calculate the position of tautomeric equilibrium in a given compound. The procedure is illustrated with reference to the tautomerism of thienol (2-hydroxythiophen), p-nitrosophenol and 4-nitroso-I-naphthol. The procedure followed rests on the adherence of many group and structural ΔRM parameters to the additivity principle of 's equation.
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