R L WOLF, M MENDLOWITZ, L J SOFFER, J ROBOZ, S E GITLOW
{"title":"METABOLISM OF CORTICOTROPIN IN MAN.","authors":"R L WOLF, M MENDLOWITZ, L J SOFFER, J ROBOZ, S E GITLOW","doi":"10.3181/00379727-119-30148","DOIUrl":null,"url":null,"abstract":"Summary Synthetic beta1-24 corticotropin has been labeled with I131 and intravenously administered to normal subjects. Analysis of the blood radioactivity following intravenous administration of beta1-24 corticotropin-I131 revealed that this substance has an apparent space of distribution of 43% of the body weight and a plasma half-life of 7 minutes.","PeriodicalId":20675,"journal":{"name":"Proceedings of the Society for Experimental Biology and Medicine","volume":" ","pages":"244-8"},"PeriodicalIF":0.0000,"publicationDate":"1965-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3181/00379727-119-30148","citationCount":"16","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Society for Experimental Biology and Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3181/00379727-119-30148","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 16
Abstract
Summary Synthetic beta1-24 corticotropin has been labeled with I131 and intravenously administered to normal subjects. Analysis of the blood radioactivity following intravenous administration of beta1-24 corticotropin-I131 revealed that this substance has an apparent space of distribution of 43% of the body weight and a plasma half-life of 7 minutes.
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