[Observational study of the tolerance and effectiveness of cefpodoxim-proxetil in general practice].

K Hanke, S P F Blum
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Abstract

BACKGROUND, OUTCOME AND METHODS: Observational study of the clinical efficacy and tolerance of the cefpodoxime proxetil preparation, Podomexef. The study was conducted from August 1996 to April 1997. A total of 549 practitioners participated, 2,734 patients were recruited, and the data of 2714 patients were analyzed.

Dosage: Podomexef 200 film tablets, 2x daily.

Indication: Bacterial infections of the upper and lower airways and ENT infections.

Results: Global clinical efficacy was assessed by the physicians to be "very good" and "good" in 96.4% of the cases. With regard to tolerance, the physicians' assessment was "very good" and "good" in 96.3%. In 51 patients (1.9%), 70 adverse drug reactions involving the gastrointestinal tract, CNS and skin occurred.

Conclusion: Under day-to-day doctor's office conditions, Podomexef 200 film tablets are both effective and well tolerated in the treatment of bacterial infections of the airways and ENT infections.

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[全科医生对头孢泊肟酯耐受性和有效性的观察研究]。
背景、结果和方法:对头孢泊肟酯制剂 Podomexef 的临床疗效和耐受性进行观察研究。研究于 1996 年 8 月至 1997 年 4 月进行。共有 549 名医生参与,2734 名患者被招募,对 2714 名患者的数据进行了分析:剂量:200片,每日2次:适应症:上下气道细菌感染和耳鼻喉科感染:结果:96.4%的病例临床疗效被医生评为 "非常好 "和 "好"。在耐受性方面,96.3%的病例被医生评为 "非常好 "和 "好"。有 51 名患者(1.9%)发生了 70 例药物不良反应,涉及胃肠道、中枢神经系统和皮肤:结论:在日常诊疗条件下,Podomexef 200 薄膜片治疗呼吸道细菌感染和耳鼻喉科感染既有效又耐受良好。
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