Awareness of genetic testing for cancer among United States Hispanics: the role of acculturation.

Community genetics Pub Date : 2008-01-01 Epub Date: 2008-01-15 DOI:10.1159/000111638
Julia E Heck, Rebeca Franco, Janine M Jurkowski, Sherri Sheinfeld Gorin
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引用次数: 35

Abstract

Background: The purpose of this study was to determine how acculturation affected awareness of genetic testing for cancer among Hispanic Americans.

Methods: Subjects were 10,883 Hispanic respondents from the 2000 and 2005 National Health Interview Surveys. Acculturation was measured with language use and the length of time subjects had lived in the US. Weighted logistic regression was used to determine subjects' awareness of genetic susceptibility testing.

Results: Greater use of English (adjusted odds ratio, OR = 1.25, 95% confidence interval, CI = 1.15-1.36) was associated with increased awareness of genetic testing. Residence in the US for less than 5 years (adjusted OR = 0.55, 95% CI 0.36-0.83) was associated with lower awareness of testing.

Conclusions: To better inform diverse American groups about genetic testing, intercultural variations and language skills must be taken into account.

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美国拉美裔人对癌症基因检测的认识:文化适应的作用。
背景:本研究的目的是确定文化适应如何影响西班牙裔美国人对癌症基因检测的认识。方法:对象为2000年和2005年全国健康访谈调查的10883名西班牙裔受访者。文化适应是通过语言使用和受试者在美国生活的时间长短来衡量的。采用加权logistic回归分析被试对遗传易感性检测的知晓程度。结果:更多地使用英语(校正优势比OR = 1.25, 95%可信区间CI = 1.15-1.36)与提高基因检测意识相关。居住在美国少于5年(调整后OR = 0.55, 95% CI 0.36-0.83)与检测意识较低相关。结论:为了更好地让不同的美国群体了解基因检测,必须考虑到文化差异和语言技能。
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