Implementation of the Prostate Cancer Prevention Trial (PCPT)

Phyllis J Goodman , Catherine M Tangen , John J Crowley , Susan M Carlin , Anne Ryan , Charles A Coltman Jr. , Leslie G Ford , Ian M Thompson
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引用次数: 30

Abstract

The Prostate Cancer Prevention Trial is a randomized double blind chemoprevention trial of 18,882 men. It is designed to test the difference in the histologically proven prostate cancer prevalence between a group of participants given finasteride and another given placebo for 7 years. We present an overview of the study design, details of the administrative structure of the study and a description of the successful implementation of the accrual phase.

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实施前列腺癌预防试验(PCPT)
前列腺癌预防试验是一项随机双盲化学预防试验,共有18882名男性参加。它的目的是测试一组服用非那雄胺和另一组服用安慰剂7年的组织学证实的前列腺癌患病率的差异。我们提出了研究设计的概述,研究的行政结构的细节和描述的成功实施权责发生制阶段。
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