Metastatic follicular dendritic cell sarcoma of the stomach: a case report and review of the literature.

IF 1.5 4区 医学 Q2 Medicine Acta Gastro-Enterologica Belgica Pub Date : 2004-04-01
A Geerts, E Lagae, K Dhaene, M Peeters, A Waeytens, P Demetter, C Cuvelier, L Defreyne, M De Vos, P Pattyn
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引用次数: 0

Abstract

Follicular dendritic cell (FDC) sarcomas are rare tumours, typically seen in lymph nodes. However, in about one third of the reported cases, a FDC sarcoma presents as an extranodal mass. Involvement of the gastrointestinal tract is extremely rare, and only 3 cases have been described to date. We report on a 40-year-old female patient with a follicular dendritic cell sarcoma located in the stomach and the presence of a metastasis in the liver at the time of diagnosis. Severe asthenia, nausea, back pain and loss of weight were the presenting symptoms. A CT scan of the abdomen and an upper gastrointestinal endoscopy revealed a tumour mass in the stomach. The diagnosis of a FDC sarcoma was made on histological and immunohistochemical findings. We report the second case of a FDC sarcoma presenting in the stomach. Due to its rarity, a FDC sarcoma seldom enters the differential diagnosis of spindle cells neoplasms of the gastrointestinal tract. Complete surgical resection is the treatment of choice for FDC sarcoma.

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胃转移性滤泡树突状细胞肉瘤一例报告及文献复习。
滤泡树突状细胞肉瘤是一种罕见的肿瘤,通常见于淋巴结。然而,在大约三分之一的报告病例中,FDC肉瘤表现为结外肿块。累及胃肠道极为罕见,迄今仅有3例被报道。我们报告一个40岁的女性患者滤泡树突状细胞肉瘤位于胃和存在转移的肝脏在诊断时。严重的虚弱、恶心、背痛和体重减轻是主要症状。腹部的CT扫描和上消化道内窥镜检查显示胃内有肿块。根据组织学和免疫组织化学结果诊断为FDC肉瘤。我们报告第二例FDC肉瘤出现在胃。由于其罕见性,FDC肉瘤很少进入胃肠道梭形细胞肿瘤的鉴别诊断。完全手术切除是FDC肉瘤的治疗选择。
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来源期刊
Acta Gastro-Enterologica Belgica
Acta Gastro-Enterologica Belgica 医学-胃肠肝病学
CiteScore
2.80
自引率
20.00%
发文量
0
审稿时长
>12 weeks
期刊介绍: The Journal Acta Gastro-Enterologica Belgica principally publishes peer-reviewed original manuscripts, reviews, letters to editors, book reviews and guidelines in the field of clinical Gastroenterology and Hepatology, including digestive oncology, digestive pathology, as well as nutrition. Pure animal or in vitro work will not be considered for publication in the Journal. Translational research papers (including sections of animal or in vitro work) are considered by the Journal if they have a clear relationship to or relevance for clinical hepato-gastroenterology (screening, disease mechanisms and/or new therapies). Case reports and clinical images will be accepted if they represent an important contribution to the description, the pathogenesis or the treatment of a specific gastroenterology or liver problem. The language of the Journal is English. Papers from any country will be considered for publication. Manuscripts submitted to the Journal should not have been published previously (in English or any other language), nor should they be under consideration for publication elsewhere. Unsolicited papers are peer-reviewed before it is decided whether they should be accepted, rejected, or returned for revision. Manuscripts that do not meet the presentation criteria (as indicated below) will be returned to the authors. Papers that go too far beyond the scope of the journal will be also returned to the authors by the editorial board generally within 2 weeks. The Journal reserves the right to edit the language of papers accepted for publication for clarity and correctness, and to make formal changes to ensure compliance with AGEB’s style. Authors have the opportunity to review such changes in the proofs.
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