INFLUENCE OF PERITONEAL INFLAMMATORY EXUDATE ON DEVELOPMENT OF A TRANSPLANTABLE MOUSE ASCITES TUMOR.

Abstract

Summary Three daily peritoneal injections of 1:1000 glycogen solution induced in mice, during at least 10 days, a state of relative resistance to intraperitoneal but not subcutaneous inoculation of homotransplantable dL-46 ascites tumor cells. Removal of excess macrophages by peritoneal washing or their transfer to untreated mice did not influence the development of dL-46 ascites. Furthermore, elaboration of specific immune reaction by intraperitoneal inoculation of irradiated cells was not enhanced in glycogen treated mice.