Sylvain Bordenave, Céline Aguer, Magali Kitzmann, Jacques Mercier
{"title":"[Physical exercise and insulin resistance: from muscle metabolic physiopathology to therapeutics].","authors":"Sylvain Bordenave, Céline Aguer, Magali Kitzmann, Jacques Mercier","doi":"10.1051/jbio:2007018","DOIUrl":null,"url":null,"abstract":"<p><p>Insulin resistance which characterises obesity and type 2 diabetes depends on genetic and environmental factors. Sedentarity plays a key role in the development of insulin resistance and skeletal muscle of obese or type 2 diabetes patients shows several abnormalities of carbohydrate and fat metabolism. Exercice training by its beneficial effects on skeletal muscle and particularly on mitochondrial function is efficient to prevent and to treat obesity and type 2 diabetes.</p>","PeriodicalId":80018,"journal":{"name":"Journal de la Societe de biologie","volume":"201 2","pages":"149-54"},"PeriodicalIF":0.0000,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1051/jbio:2007018","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal de la Societe de biologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1051/jbio:2007018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Insulin resistance which characterises obesity and type 2 diabetes depends on genetic and environmental factors. Sedentarity plays a key role in the development of insulin resistance and skeletal muscle of obese or type 2 diabetes patients shows several abnormalities of carbohydrate and fat metabolism. Exercice training by its beneficial effects on skeletal muscle and particularly on mitochondrial function is efficient to prevent and to treat obesity and type 2 diabetes.
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