Genomics and biology of the nematode Caenorhabditis briggsae.

Bhagwati P Gupta, Robert Johnsen, Nansheng Chen
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引用次数: 53

Abstract

The soil nematode Caenorhabditis briggsae is an attractive model system for studying evolution of both animal development and behavior. Being a close relative of C. elegans, C. briggsae is frequently used in comparative studies to infer species-specific function of the orthologous genes and also for studying the dynamics of chromosome evolution. The genome sequence of C. briggsae is valuable in reverse genetics and genome-wide comparative studies. This review discusses resources and tools, which are currently available, to facilitate study of C. briggsae in order to unravel mechanisms of gene function that confer morphological and behavioral diversity.

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briggsae隐杆线虫的基因组学和生物学。
土壤线虫是研究动物发育和行为进化的一个有吸引力的模型系统。作为秀丽隐杆线虫的近亲,秀丽隐杆线虫经常被用于比较研究,以推断其同源基因的物种特异性功能,也用于研究染色体进化的动力学。该菌株的基因组序列在逆向遗传和全基因组比较研究中具有重要的应用价值。本文综述了现有的资源和工具,以促进对金丝桃的研究,以揭示赋予形态和行为多样性的基因功能机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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