Polymelia (thoracomelia), an extremely rare appearance of congenital anomalic limb in a Nepalese child and its embryological basis.

IF 1.4 Q3 ANATOMY & MORPHOLOGY Anatomy & Cell Biology Pub Date : 2023-12-31 Epub Date: 2023-09-27 DOI:10.5115/acb.23.179
Ameet Kumar Jha, Samal Nauhria, Sabyasachi Maity
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Abstract

Polymelia is an extremely rare congenital anomaly where an individual is born with an abnormally developed extra or supernumerary limb which is generally shrunken and functionless. A case of thoracomelia (a type of polymelia) was observed macroscopically and confirmed radiologically in 1.5 years old boy born in Nepal with an abnormal supernumerary upper limb attached to his back in the thoracic region. The limb was successfully amputated, and the boy had a favorable outcome after surgical treatment, without any adverse effects or impairment. Understanding the embryogenesis of thoracomelia is essential for unraveling the complex mechanisms underlying this condition and potentially aiding in early diagnosis and intervention. This case report and review aims to shed light on the intricate processes governing forelimb formation and their perturbations leading to thoracomelia.

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多聚体细胞增多症,尼泊尔儿童先天性畸形肢体的一种极为罕见的表现及其胚胎学基础。
多聚体细胞瘤是一种极为罕见的先天性异常,个体出生时有异常发育的多生或多生肢体,通常萎缩且无功能。在尼泊尔出生的一名1.5岁男孩中,通过肉眼观察和放射学证实了一例胸腔积液(一种多聚体),他的背部胸部有异常的多生上肢。截肢成功,男孩在手术治疗后取得了良好的结果,没有任何不良反应或损伤。了解胸鼻疽的胚胎发生对于揭示这种疾病的复杂机制至关重要,并有助于早期诊断和干预。本病例报告和综述旨在阐明前肢形成的复杂过程及其导致胸脯畸形的扰动。
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来源期刊
Anatomy & Cell Biology
Anatomy & Cell Biology ANATOMY & MORPHOLOGY-
CiteScore
1.80
自引率
9.10%
发文量
75
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