Topical Roflumilast for Plaque Psoriasis.

Q1 Medicine Skin therapy letter Pub Date : 2023-09-01
Ashley O'Toole, Melinda Gooderham
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引用次数: 0

Abstract

Roflumilast is a highly selective phosphodiesterase-4 inhibitor for the treatment of plaque psoriasis. Topical roflumilast 0.3% cream, approved by the US FDA and Health Canada for use in adolescents and adults, has proven efficacy and tolerability. It is non-steroidal, administered once-daily, and highly potent, with a unique delivery formulation. It can be used on most body areas, including the sensitive intertriginous regions and face. Herein, we review the safety and efficacy of roflumilast 0.3% cream, as demonstrated in clinical trials.

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局部罗氟司特治疗斑块型银屑病。
罗氟司特是一种高选择性磷酸二酯酶-4抑制剂,用于治疗斑块型银屑病。经美国食品药品监督管理局和加拿大卫生部批准用于青少年和成人的0.3%罗氟司特局部乳膏已被证明具有疗效和耐受性。它是非甾体的,每天给药一次,药效很强,具有独特的递送配方。它可以用于大多数身体部位,包括敏感的原始区域和面部。在此,我们回顾了临床试验中证明的0.3%罗氟司特乳膏的安全性和有效性。
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来源期刊
Skin therapy letter
Skin therapy letter Medicine-Medicine (all)
CiteScore
2.80
自引率
0.00%
发文量
0
期刊介绍: The premier international journal on the latest advances, techniques and practice in conservation and restoration from around the world.
期刊最新文献
Icotrokinra: A Promising Oral IL-23 Receptor Inhibitor for Moderate-to-Severe Plaque Psoriasis. Deuruxolitinib for Alopecia Areata. OX40 Ligand Inhibitors for Moderate-to-Severe Atopic Dermatitis: A Review of Phase II Clinical Trial Data. Neoadjuvant Immunotherapy in the Management of Cutaneous Squamous Cell Carcinoma. A Review of the Long-Term Safety and Efficacy of Upadacitinib in the Treatment of Atopic Dermatitis.
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