Association of Insomnia with Anxiety and Depression in Type 2 Diabetic Patients: A Cross-Sectional Study.

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Iranian Journal of Medical Sciences Pub Date : 2023-09-01 DOI:10.30476/ijms.2023.96017.2755

Karlyghash Shinalieva, Asemgul Kasenova, Zauresh Akhmetzhanova, Dinara Alzhanova, Laura Eszhanova, Ainur Bekenova

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Abstract

Background: Type 2 diabetes mellitus (T2DM) is associated with sleep disorders, which in turn may lead to anxiety and depression. Sleep deprivation impairs glucose metabolism causing a decrease in insulin sensitivity and glucose tolerance. The present study aimed to determine the association of insomnia with anxiety and depression in patients with T2DM.

Methods: A cross-sectional study was conducted in 2020 at the Endocrinological Department of City Clinical Hospital №1, affiliated with Astana Medical University (Astana, Kazakhstan). A total of 376 patients with decompensated T2DM were included in the study. Insomnia was assessed using the Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI). Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS). Multivariable logistic regression was used to assess the association of insomnia with anxiety and depression.

Results: All patients showed signs of sleep disturbances. Based on the HADS cutoff score >8, anxiety and depression were observed in 48 (12.80%) and 46 (12.20%) patients, respectively. PSQI, ISI, and HADS indicators were associated with an increased risk of anxiety and depression symptoms. In terms of anxiety, the adjusted odds ratio for PSQI and ISI scores were 1.09 (P=0.08) and 1.07 (P=0.01), respectively. These for depression were 1.10 (P=0.06) and 1.07 (P=0.01), respectively.

Conclusion: Sleep quality is an important indicator of psychological health in patients with T2DM, especially those who exhibit signs of anxiety and depression.

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2型糖尿病患者失眠与焦虑和抑郁的关系：一项横断面研究。

背景：2型糖尿病（T2DM）与睡眠障碍有关，而睡眠障碍又可能导致焦虑和抑郁。睡眠不足会损害葡萄糖代谢，导致胰岛素敏感性和糖耐量下降。本研究旨在确定T2DM患者失眠与焦虑和抑郁的关系。方法：2020年在城市临床医院内分泌科进行了一项横断面研究№1，隶属于阿斯塔纳医科大学（哈萨克斯坦阿斯塔纳）。本研究共纳入376例失代偿期T2DM患者。使用匹兹堡睡眠质量指数（PSQI）和失眠严重程度指数（ISI）评估失眠。使用医院焦虑和抑郁量表（HADS）评估焦虑和抑郁。多变量逻辑回归用于评估失眠与焦虑和抑郁的关系。结果：所有患者均出现睡眠障碍症状。基于HADS临界分数>8，分别在48名（12.80%）和46名（12.20%）患者中观察到焦虑和抑郁。PSQI、ISI和HADS指标与焦虑和抑郁症状的风险增加有关。在焦虑方面，PSQI和ISI评分的调整比值比分别为1.09（P=0.08）和1.07（P=0.01）。抑郁症的发病率分别为1.10（P=0.06）和1.07（P=0.01）。结论：睡眠质量是2型糖尿病患者心理健康的重要指标，尤其是那些表现出焦虑和抑郁症状的患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Medical Sciences MEDICINE, GENERAL & INTERNAL-

CiteScore

3.20

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： The Iranian Journal of Medical Sciences (IJMS) is an international quarterly biomedical publication, which is sponsored by Shiraz University of Medical Sciences. The IJMS intends to provide a scientific medium of communication for researchers throughout the globe. The journal welcomes original clinical articles as well as clinically oriented basic science research experiences on prevalent diseases in the region and analysis of various regional problems.