[Application and advances of nanozyme-loaded tissue engineering scaffolds in wound repair].

R N Hao, X L Ye, B L Xu, Y Sun, H Y Liu, F Rao, J J Xue
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Abstract

At present, effective reconstruction of the integrity and functionality of damaged skin tissue remains an important medical problem in the field of wound repair. In recent years, the rapid development of nanozymes and tissue engineering scaffolds in the field of regenerative medicine has made it possible to develop new skin wound repair materials. Based on the process of skin wound repair and regeneration, this review briefly describes the nanozymes and its catalytic mechanism. At the same time, the common tissue engineering scaffolds loaded with nanozymes and their manufacturing strategies are introduced, the application of tissue engineering scaffolds loaded with nanozymes during the stages of anti-bacteria and anti-inflammation in the process of wound repair is summarized, and their future development direction is discussed.

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【纳米酶负载组织工程支架在创伤修复中的应用与进展】。
目前,有效重建受损皮肤组织的完整性和功能仍然是伤口修复领域的一个重要医学问题。近年来,纳米酶和组织工程支架在再生医学领域的快速发展,为开发新的皮肤创伤修复材料提供了可能。本文从皮肤创伤修复和再生的过程出发,简要介绍了纳米酶及其催化机制。同时,介绍了常见的负载纳米酶的组织工程支架及其制备策略,总结了负载纳米酶组织工程支架在创伤修复过程中抗菌抗炎阶段的应用,并探讨了其未来的发展方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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期刊介绍: The Chinese Journal of Burns is the most authoritative one in academic circles of burn medicine in China. It adheres to the principle of combining theory with practice and integrating popularization with progress and reflects advancements in clinical and scientific research in the field of burn in China. The readers of the journal include burn and plastic clinicians, and researchers focusing on burn area. The burn refers to many correlative medicine including pathophysiology, pathology, immunology, microbiology, biochemistry, cell biology, molecular biology, and bioengineering, etc. Shock, infection, internal organ injury, electrolytes and acid-base, wound repair and reconstruction, rehabilitation, all of which are also the basic problems of surgery.
期刊最新文献
[A case of severe acute respiratory distress syndrome caused by inhalation injury]. [A randomized controlled trial on the effect of exercise prescription based on a progressive mode in treating elderly patients with lower limb dysfunction after deep burns]. [Anatomical study of the architecture of the cutaneous branch-chained blood vessels in the medial lower leg in adult]. [Clinical effect of free posterior interosseous artery perforator flap carrying superficial vein for reconstructing severe perioral scar hyperplasia and contracture]. [Clinical effects of different types of tissue flaps in repairing the wounds with steel plate exposure and infection after proximal tibial fracture surgery].
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