[Research advances on conductive hydrogels and their applications in the repair of diabetic wounds].

Y Lyu, W L Chu, Y Chen, Y J Li, X L Ma
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Abstract

As a new type of functional wound dressing, conductive hydrogel, shows broad prospects of application in the field of wound repair due to its suitable electrical conductivity, good moisture retention, excellent biocompatibility, and biological effects such as mediating cell migration and proliferation, and promoting angiogenesis and collagen deposition. Combined with the clinical electrical stimulation therapy, the conductive hydrogel primarily showed curative effects of promoting granulation tissue formation, re-epithelialization, and wound healing, providing a new treatment idea for the repair of diabetic wounds. This review summarized the research advances of electronic conductive hydrogels and ionic conductive hydrogels in recent years based on different conductive mechanisms. Meanwhile, the applications of conductive hydrogel in the diabetic wound repair were specifically introduced, and the future development of conductive hydrogel wound dressing was prospected.

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【导电水凝胶及其在糖尿病伤口修复中的应用研究进展】。
导电水凝胶作为一种新型的功能性创伤敷料,由于其具有合适的导电性、良好的保湿性、优异的生物相容性以及介导细胞迁移和增殖、促进血管生成和胶原沉积等生物学效应,在创伤修复领域显示出广阔的应用前景。结合临床电刺激治疗,该导电水凝胶初步显示出促进肉芽组织形成、上皮再形成和伤口愈合的疗效,为糖尿病伤口修复提供了新的治疗思路。综述了近年来基于不同导电机理的电子导电水凝胶和离子导电水凝胶的研究进展。同时,具体介绍了导电水凝胶在糖尿病创面修复中的应用,并对导电水凝胶创面敷料的未来发展进行了展望。
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期刊介绍: The Chinese Journal of Burns is the most authoritative one in academic circles of burn medicine in China. It adheres to the principle of combining theory with practice and integrating popularization with progress and reflects advancements in clinical and scientific research in the field of burn in China. The readers of the journal include burn and plastic clinicians, and researchers focusing on burn area. The burn refers to many correlative medicine including pathophysiology, pathology, immunology, microbiology, biochemistry, cell biology, molecular biology, and bioengineering, etc. Shock, infection, internal organ injury, electrolytes and acid-base, wound repair and reconstruction, rehabilitation, all of which are also the basic problems of surgery.
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