Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin's Lymphoma.

IF 3.3 3区 医学 Q2 CHEMISTRY, MEDICINAL Mini reviews in medicinal chemistry Pub Date : 2024-01-01 DOI:10.2174/1389557523666230915103121
Shuxian Liu, Minghao Xu, Lei Zhong, Xiangmin Tong, Suying Qian
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Abstract

Lymphoma is the eighth most common type of cancer worldwide. Currently, lymphoma is mainly classified into two main groups: Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL), with NHL accounting for 80% to 90% of the cases. NHL is primarily divided into B, T, and natural killer (NK) cell lymphoma. Nanotechnology is developing rapidly and has made significant contributions to the field of medicine. This review summarizes the advancements of nanobiotechnology in recent years and its applications in the treatment of NHL, especially in diffuse large B cell lymphoma (DLBCL), primary central nervous system lymphoma (PCNSL), and follicular lymphoma (FL). The technologies discussed include clinical imaging, targeted drug delivery, photodynamic therapy (PDT), and thermodynamic therapy (TDT) for lymphoma. This review aims to provide a better understanding of the use of nanotechnology in the treatment of non-Hodgkin's lymphoma.

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纳米生物技术治疗非霍奇金淋巴瘤的最新进展。
淋巴瘤是全球第八大常见的癌症。目前,淋巴瘤主要分为两大类:霍奇金淋巴瘤(HL)和非霍奇金淋巴瘤(NHL),其中NHL占80%至90%的病例。NHL主要分为B细胞淋巴瘤、T细胞淋巴瘤和自然杀伤细胞淋巴瘤。纳米技术发展迅速,对医学领域做出了重大贡献。本文综述了近年来纳米生物技术的进展及其在NHL治疗中的应用,特别是在弥漫性大B细胞淋巴瘤(DLBCL)、中枢神经细胞淋巴瘤和滤泡性淋巴瘤中的应用。讨论的技术包括临床成像、靶向药物递送、光动力疗法(PDT)和淋巴瘤的热力学疗法。这篇综述旨在更好地了解纳米技术在非霍奇金淋巴瘤治疗中的应用。
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来源期刊
CiteScore
7.80
自引率
0.00%
发文量
231
审稿时长
6 months
期刊介绍: The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines. Mini-Reviews in Medicinal Chemistry covers all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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