A patient with Marchiafava–Bignami disease type A transported by ambulance with impaired consciousness and malnutrition was successfully treated after early diagnosis by MRI

IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Journal of General and Family Medicine Pub Date : 2023-07-20 DOI:10.1002/jgf2.636

Yoshitaka Ooya M.D., Ph.D., Mayumi Ishida C.P., Ph.D., Nozomu Uchida M.D., Ryota Sato M.S., Akira Yoshioka M.D., Ph.D., Izumi Sato MPH, Ph.D., Hideki Onishi M.D., Ph.D.

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Abstract

Marchiafava–Bignami disease (MBD) is a very rare disorder characterized by demyelination and necrosis of the corpus callosum.

A 53-year-old male was transported to the emergency room with impaired consciousness. On his arrival, he was quite emaciated. CT examination revealed no hemorrhagic lesions whereas MR images showed hyperintense areas throughout the corpus callosum, leading to a diagnosis of MBD. His impaired consciousness improved with treatment, including parenteral thiamine administration.

When examining patients with impaired consciousness because of malnutrition, MBD should be taken in consideration and the incorporation of head MR imaging into the examination protocol enables early diagnosis and treatment, and may improve the prognosis.

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一名意识受损、营养不良的A型Marchiafava Bignami病患者，经MRI早期诊断，成功治疗。

Marchiafava Bignami病（MBD）是一种非常罕见的疾病，其特征是胼胝体脱髓鞘和坏死。一名53岁男性因意识受损被送往急诊室。他一到就很消瘦。CT检查显示没有出血性病变，而MR图像显示整个胼胝体的高信号区域，从而诊断为MBD。他受损的意识通过治疗得到改善，包括胃肠外给药硫胺素。在检查因营养不良而意识受损的患者时，应考虑MBD，将头部MR成像纳入检查方案可以早期诊断和治疗，并可能改善预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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