A Bayesian nonparametric approach to correct for underreporting in count data.

IF 1.8 3区 数学 Q3 MATHEMATICAL & COMPUTATIONAL BIOLOGY Biostatistics Pub Date : 2024-07-01 DOI:10.1093/biostatistics/kxad027
Serena Arima, Silvia Polettini, Giuseppe Pasculli, Loreto Gesualdo, Francesco Pesce, Deni-Aldo Procaccini
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Abstract

We propose a nonparametric compound Poisson model for underreported count data that introduces a latent clustering structure for the reporting probabilities. The latter are estimated with the model's parameters based on experts' opinion and exploiting a proxy for the reporting process. The proposed model is used to estimate the prevalence of chronic kidney disease in Apulia, Italy, based on a unique statistical database covering information on m = 258 municipalities obtained by integrating multisource register information. Accurate prevalence estimates are needed for monitoring, surveillance, and management purposes; yet, counts are deemed to be considerably underreported, especially in some areas of Apulia, one of the most deprived and heterogeneous regions in Italy. Our results agree with previous findings and highlight interesting geographical patterns of the disease. We compare our model to existing approaches in the literature using simulated as well as real data on early neonatal mortality risk in Brazil, described in previous research: the proposed approach proves to be accurate and particularly suitable when partial information about data quality is available.

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一种贝叶斯非参数方法,用于纠正计数数据中的漏报。
我们提出了一个用于少报计数数据的非参数复合泊松模型,该模型引入了报告概率的潜在聚类结构。后者是根据专家的意见和报告过程中的代理使用模型参数进行估计的。所提出的模型用于估计意大利阿普利亚的慢性肾脏疾病患病率,基于一个独特的统计数据库,该数据库涵盖了通过整合多源登记信息获得的m=258个市镇的信息。为了监测、监测和管理目的,需要准确的流行率估计;然而,统计数字被认为被严重低估,尤其是在意大利最贫困、最异质的地区之一阿普利亚的一些地区。我们的研究结果与之前的发现一致,并突出了该疾病有趣的地理模式。我们使用先前研究中描述的巴西早期新生儿死亡率风险的模拟和真实数据,将我们的模型与文献中的现有方法进行了比较:当获得有关数据质量的部分信息时,所提出的方法被证明是准确的,特别适合。
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来源期刊
Biostatistics
Biostatistics 生物-数学与计算生物学
CiteScore
5.10
自引率
4.80%
发文量
45
审稿时长
6-12 weeks
期刊介绍: Among the important scientific developments of the 20th century is the explosive growth in statistical reasoning and methods for application to studies of human health. Examples include developments in likelihood methods for inference, epidemiologic statistics, clinical trials, survival analysis, and statistical genetics. Substantive problems in public health and biomedical research have fueled the development of statistical methods, which in turn have improved our ability to draw valid inferences from data. The objective of Biostatistics is to advance statistical science and its application to problems of human health and disease, with the ultimate goal of advancing the public''s health.
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