Value of [18F]FDG PET/CT in Diagnosis and Management of Spondylodiscitis.

Zeitschrift fur Orthopadie und Unfallchirurgie Pub Date : 2023-10-01 Epub Date: 2023-09-28 DOI:10.1055/a-2075-8873
Constantin Lapa, Christoph Rischpler, Ralph Alexander Bundschuh, Alexander Dierks, Sigmund Lang, Georgi Wassilew, Volker Alt
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Abstract

Vertebral osteomyelitis is the third most common form of osteomyelitis in patients over 50 years of age.Whereas prompt (pathogen-directed) therapy is crucially associated with better outcomes, the heterogeneous clinical presentation of disease with unspecific symptoms often delays adequate treatment initiation. Diagnosis requires a careful investigation of medical history, clinical findings and diagnostic imaging, including magnetic resonance imaging and nuclear medicine techniques.Due to its high sensitivity, [18F]FDG PET/CT is becoming increasingly important in diagnosis and management of spondylodiscitis, especially in the postoperative setting with presence of spinal hardware or other implantable devices in which MRI is limited.

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[18F]FDG PET/CT在脊椎骨炎诊断和治疗中的价值。
脊椎骨髓炎是50岁以上患者中第三常见的骨髓炎。尽管及时(病原体导向)治疗与更好的结果至关重要,但具有非特异性症状的疾病的异质性临床表现往往会延迟充分的治疗开始。诊断需要仔细调查病史、临床表现和诊断成像,包括磁共振成像和核医学技术。由于其高灵敏度,[18F]FDG PET/CT在椎间盘炎的诊断和治疗中变得越来越重要,尤其是在MRI有限的脊柱硬件或其他植入式设备的术后环境中。
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