Clinical Analysis of 3D-Fluid Attenuated Inversion Recovery and T1volume interpolated body examination Sequences on Delayed Gadolinium-Enhanced Scanning in Ramsay Hunt Syndrome.

Yonping Han, Lei Lui, Junyi Zhang, Xueqin Du, Wenjie Fan
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Abstract

Background: Through the clinical analysis of 4 clinically confirmed cases of delayed gadolinium enhancement of Ramsay Hunt syndrome 3D-Fluid Attenated Inversion Recovery'and 'T1volume interpolated body examination (3D-FLAIR and T1VIBE) sequences, the more suitable sequences and pathologically damaged tissue sites of deep tissues of Ramsay Hunt syndrome by magnetic resonance imaging gadolinium enhancement were preliminarily explored.

Methods: From October 2020 to March 2021, 4 clinically confirmed patients with Ramsay Hunt syndrome, 2 males and 2 females, aged 27-63, were continuously collected in the hospital otology clinic. Siemens Avento 1.5T magnetic resonance imaging 3D-FLAIR and T1VIBE sequencedelayed gadolinium enhancement scans and serological laboratory tests were performed, respectively, and corresponding antiviral and antiinflammatory therapy was given.

Results: The magnetic resonance imaging gadolinium enhancement of 4 cases of Ramsay Hunt syndrome was as follows: 3D-FLAIR sequence delay of 4.5 hours scanning 4 patients labyrinthine and/or middle ear signal was enhanced at the same time as the healthy side; T1VIBE sequence scanning disease in 3 cases of vestibular nerve development was enhanced than the healthy side, 2 cases of facial nerve development was enhanced than the healthy side, and 2 cases of cochlear nerve development was enhanced than the healthy side. All 4 patients were cured with related treatment.

Conclusion: Through the comparison of 3D-FAIR and T1VIBE sequence of 4.5 hours delay before intravenous gadolinium injection and 4.5 hours delay after intravenous gadolinium injection in 4 patients with Ramsay Hunt syndrome, it was found that (i) 3D-FLAIR sequence delay of 4.5 hours scan was more likely to show whether the inner ear labyrinth barrier permeability increased and (ii) Ramsay Hunt syndrome deep ear tissue damage can be manifested as labyrinthitis, vestibular cochlear neuritis, facial neuritis, and otitis media.

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Ramsay-Hunt综合征延迟钆增强扫描三维液体衰减倒置恢复和T1容积内插身体检查序列的临床分析。
背景:通过对4例临床确诊的Ramsay-Hunt综合征延迟钆增强患者的临床分析,采用3D-FLAIR和T1VIBE序列,初步探讨了磁共振成像钆增强对Ramsay-Hunt综合征深部组织更合适的序列和病理损伤部位。方法:自2020年10月至2021年3月,在医院耳科门诊连续收集4例临床确诊的拉姆齐-亨特综合征患者,2男2女,年龄27-63岁。分别进行Siemens Avento 1.5T磁共振成像3D-FLAIR和T1VIBE序列的钆增强扫描和血清学实验室测试,并给予相应的抗病毒和抗炎治疗。结果:4例Ramsay-Hunt综合征患者的磁共振钆增强表现为:3D-FLAIR序列延迟4.5小时扫描4例患者的迷路和/或中耳信号与健康侧同时增强;T1VIBE序列扫描病变3例前庭神经发育比健康侧增强,2例面神经发展比健康侧加强,2例耳蜗神经发展比正常侧加强。经相关治疗,4例患者全部治愈。结论:通过对4例Ramsay-Hunt综合征患者静脉注射钆前延迟4.5小时和静脉注射后延迟4.5小时的3D-FAIR和T1VIBE序列的比较,发现(i)4.5小时扫描的3D-FLAIR序列延迟更有可能显示内耳迷路屏障通透性是否增加,以及(ii)Ramsay-Hunt综合征深耳组织损伤可表现为迷路炎、前庭耳蜗神经炎、面神经炎和中耳炎。
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