Characteristics And Outcome Influence Of Increased Plasma Triglyceride Level In Severely Burned Adult Patients.

Annals of burns and fire disasters Pub Date : 2021-06-30
N N Lam, P Q Khanh, N H An
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Abstract

The aims of this study were to investigate the profile of serum triglyceride level and its influence on outcomes in adult patients with severe burns. An observational study was conducted on 62 patients with burn extent from and over 20% TBSA. Results indicated that serum triglyceride level steadily increased from 1.9mmo/l on the 3rd day to 2.5 mmol/l on the 14th day before reducing on the 21st day after burn. Remarkably higher triglyceride level was seen in patients with full thickness burn area >20% TBSA and in inhalation injury (p < .05). Liver size significantly increased over time and was greater in increased triglyceride patients, but the difference was not significant (p > .05). In addition, patients with elevated serum triglyceride level had significantly higher rates of multiple organ failure and death compared with the remaining group. Further studies need to be conducted to understand and determine intervention for increased plasma triglyceride levels in severely burned patients.

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严重烧伤成人患者血浆甘油三酯水平升高的特点及对预后的影响。
本研究的目的是研究成年严重烧伤患者血清甘油三酯水平及其对预后的影响。一项观察性研究对62名烧伤程度在20%及以上的TBSA患者进行了研究。结果表明,烧伤后血清甘油三酯水平从第3天的1.9mmol/l稳定上升到第14天的2.5mmol/l,然后在第21天下降。全层烧伤面积>20%TBSA和吸入性损伤患者的甘油三酯水平显著升高(p<0.05)。随着时间的推移,肝脏体积显著增加,甘油三酯增加的患者肝脏体积更大,但差异不显著(p>0.05)。此外,血清甘油三酯水平升高的患者与其余组相比,多器官衰竭和死亡的发生率明显更高。需要进行进一步的研究,以了解和确定严重烧伤患者血浆甘油三酯水平升高的干预措施。
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