Local Administration of Antibiotics in Orthopedics and Traumatology.

IF 0.9 Zeitschrift fur Orthopadie und Unfallchirurgie Pub Date : 2023-10-01 Epub Date: 2023-09-28 DOI:10.1055/a-1989-0565
Yves Gramlich, Matthias Schnetz, Reinhard Hoffmann
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Abstract

2022 marks the 50th anniversary of the development of the antibiotic loaded PMMA chain. The loading of bone cements with antibiotics was a major advance in the treatment of musculoskeletal infections and is still a proven standard today. The research and use of novel antibiotic carriers continues to be an important part of research in the context of musculoskeletal infections. The article provides an overview of the various local antibiotics available and their specifics. In addition, current adapted treatment concepts are discussed.

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骨科和创伤科抗生素的地方管理。
2022年是抗生素负载PMMA链开发50周年。在骨水泥中加入抗生素是治疗肌肉骨骼感染的一项重大进步,至今仍是一种经过验证的标准。新型抗生素载体的研究和使用仍然是肌肉骨骼感染研究的重要组成部分。这篇文章提供了各种可用的当地抗生素及其特点的概述。此外,目前适应的治疗概念进行了讨论。
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