Statical Association between Clinical and Histopathological Parameters for Keratinocyte Carcinomas.

Current health sciences journal Pub Date : 2023-04-01 Epub Date: 2023-06-30 DOI:10.12865/CHSJ.49.02.237
Alin Cristian Badiu, Cristiana Eugenia Simionescu, Alex Emilian Stepan, Claudiu Mărgăritescu, Mirela Marinela Florescu, Bianca Cătălina Andreiana, Anne-Marie Badiu, Oana Iulia Crețu, Andrei Muraru, Cristina Geormăneanu, Raluca Niculina Ciurea
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Abstract

The most common tumor of the western world is comprised of forms of non-melanoma skin cancers, previously known as keratinocyte carcinomas (KCs) The purpose of this study was to determine de incidence of non-melanoma skin tumors and the relationship between histopathological risk factors in patients with skin cancers. The study was composed from 332 cases of skin malignancies for which clinical and histopathological aggressivity factors were statistically analyzed through comparison tests and also stored digitally. For basal cell carcinoma (BCC) statistical analysis indicated significant relationships between pT category and gender, tumor size, ulceration, depth of invasion and positive resection limits. For squamous cell carcinoma (SCC) statistical analysis indicated significant relationships between pT category and tumor size, depth of invasion and positive resection limits. Clinical and histological analysis of certain characteristics of the above-mentioned skin cancers is an essential step in documenting and improving both prognosis and therapy standards.

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角质形成细胞癌的临床和组织病理学参数之间的统计学关联。
西方世界最常见的肿瘤是非黑色素瘤皮肤癌,以前称为角质形成细胞癌(KCs)。本研究的目的是确定非黑色素癌皮肤肿瘤的发病率以及皮肤癌患者组织病理学危险因素之间的关系。该研究由332例皮肤恶性肿瘤组成,通过比较测试对其临床和组织病理学侵袭性因素进行了统计分析,并进行了数字存储。对于基底细胞癌(BCC),统计分析表明pT类别与性别、肿瘤大小、溃疡、侵袭深度和阳性切除限度之间存在显著关系。对于鳞状细胞癌(SCC),统计分析表明pT类别与肿瘤大小、侵袭深度和阳性切除限度之间存在显著关系。对上述皮肤癌的某些特征进行临床和组织学分析是记录和改善预后和治疗标准的重要步骤。
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