{"title":"Eosinophilic-Associated Disease Overlap: What Do We Know About It?","authors":"Noeul Kang, Tae-Bum Kim","doi":"10.4168/aair.2023.15.5.539","DOIUrl":null,"url":null,"abstract":"https://e-aair.org Over the past two decades, it was discovered that a range of inflammatory diseases involving several organ systems with elevated eosinophil counts in blood and/or tissue was primarily driven by abnormal regulation of the number and activation state of eosinophils.1-11 Eosinophil-associated diseases (EADs) refer to these heterogeneous conditions in which eosinophils are believed to play critical pathological roles.1,12-14 EADs encompass common respiratory and dermatologic conditions, such as asthma,3-5 chronic rhinosinusitis with nasal polyps,6 and atopic dermatitis,7 less common eosinophilic gastrointestinal diseases,8 and rare conditions including allergic bronchopulmonary aspergillosis (ABPA),9 eosinophilic granulomatosis with polyangiitis (EGPA)1 and hypereosinophilic syndromes (HES).10","PeriodicalId":7547,"journal":{"name":"Allergy, Asthma & Immunology Research","volume":"15 5","pages":"539-542"},"PeriodicalIF":4.1000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b7/60/aair-15-539.PMC10570782.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Allergy, Asthma & Immunology Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4168/aair.2023.15.5.539","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ALLERGY","Score":null,"Total":0}
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Abstract
https://e-aair.org Over the past two decades, it was discovered that a range of inflammatory diseases involving several organ systems with elevated eosinophil counts in blood and/or tissue was primarily driven by abnormal regulation of the number and activation state of eosinophils.1-11 Eosinophil-associated diseases (EADs) refer to these heterogeneous conditions in which eosinophils are believed to play critical pathological roles.1,12-14 EADs encompass common respiratory and dermatologic conditions, such as asthma,3-5 chronic rhinosinusitis with nasal polyps,6 and atopic dermatitis,7 less common eosinophilic gastrointestinal diseases,8 and rare conditions including allergic bronchopulmonary aspergillosis (ABPA),9 eosinophilic granulomatosis with polyangiitis (EGPA)1 and hypereosinophilic syndromes (HES).10
期刊介绍：
The journal features cutting-edge original research, brief communications, and state-of-the-art reviews in the specialties of allergy, asthma, and immunology, including clinical and experimental studies and instructive case reports. Contemporary reviews summarize information on topics for researchers and physicians in the fields of allergy and immunology. As of January 2017, AAIR do not accept case reports. However, if it is a clinically important case, authors can submit it in the form of letter to the Editor. Editorials and letters to the Editor explore controversial issues and encourage further discussion among physicians dealing with allergy, immunology, pediatric respirology, and related medical fields. AAIR also features topics in practice and management and recent advances in equipment and techniques for clinicians concerned with clinical manifestations of allergies and pediatric respiratory diseases.
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