Toxicity Mechanism of Dangerous Scorpion Stings in Iran.

IF 0.6 4区医学 Q4 PARASITOLOGY Journal of Arthropod-Borne Diseases Pub Date : 2023-06-30 eCollection Date: 2023-06-01 DOI:10.18502/jad.v17i2.13616

Rouhullah Dehghani, Ahmad Ghorbani, Masoomeh Varzandeh, Fatemeh Karami-Robati

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Abstract

Background: Considering the importance of scorpions and recognizing the mechanisms of toxicity caused by their medically important species in Iran and adopting the best therapeutic approach based on these mechanisms, this study was performed by reviewing the clinical manifestations of scorpion stings.

Methods: The research was conducted by searching for articles and researches in related websites (PubMed, EMBASE, Scopus, Web of Science and CINAHL) and using domestic and international authoritative journals using the keywords of scorpion, clinical manifestations, in a review method. Finally, 104 qualified sources were selected and after reviewing and criticizing these studies, the author's point of view was presented.

Results: Clinical manifestations of Scorpion sting toxicity vary due to the existence of two toxic classes of neurotoxins and cytotoxins or hemotoxins in these arthropods in Iran. The number and distribution of species with neurotoxic venom are higher than the scorpions with cytotoxic venom and are reported throughout Iran. Scorpions with cytotoxic venom are mostly widespread in south and southwest of Iran.

Conclusion: Treatment and prevention of scorpion stings in Iran and neighboring countries in the Middle East should be planned based on the mechanism of toxicity and the presence of toxic classes with neurotoxic or cytotoxic venoms.

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伊朗危险蝎子毒刺的毒性机制。

背景：考虑到蝎子的重要性，认识到其在伊朗医学上重要的物种引起的毒性机制，并基于这些机制采取最佳治疗方法，本研究通过回顾蝎子蜇伤的临床表现来进行。方法：通过检索相关网站（PubMed、EMBASE、Scopus、Web of Science和CINAHL）上的文章和研究，并使用国内外权威期刊，以scorpion、临床表现为关键词，采用综述法进行研究。最后，选择了104个合格的来源，在对这些研究进行回顾和批评后，提出了作者的观点。结果：在伊朗，蝎子蜇伤的临床表现各不相同，这是由于这些节肢动物中存在两类毒性神经毒素和细胞毒素或血液毒素。具有神经毒性毒液的物种的数量和分布高于具有细胞毒性毒液的蝎子，并且在伊朗各地都有报道。具有细胞毒性毒素的蝎子主要分布在伊朗南部和西南部。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Arthropod-Borne Diseases PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-PARASITOLOGY

CiteScore

2.00

自引率

11.10%

发文量

审稿时长

8 weeks

期刊介绍： The journal publishes original research paper, short communication, scientific note, case report, letter to the editor, and review article in English. The scope of papers comprises all aspects of arthropod borne diseases including: ● Systematics ● Vector ecology ● Epidemiology ● Immunology ● Parasitology ● Molecular biology ● Genetics ● Population dynamics ● Toxicology ● Vector control ● Diagnosis and treatment and other related subjects.