Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report.

IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING World journal of radiology Pub Date : 2023-09-28 DOI:10.4329/wjr.v15.i9.274

Li-Hong Liu, Han-Wen Zhang, Hong-Bo Zhang, Xiao-Lei Liu, Hua-Zhen Deng, Fan Lin, Biao Huang

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Abstract

Background: Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics.

Case summary: Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy.

Conclusion: This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management.

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原发性中枢神经系统淋巴瘤的独特磁共振成像特征：一例报告。

背景：原发性中枢神经系统淋巴瘤（PCNSL）是一种罕见的起源于淋巴造血系统的恶性肿瘤。由于其生物学特性，它表现出独特的影像学表现。病例总结：进行磁共振成像（MRI）、弥散加权成像（DWI）、灌注加权成像（PWI）和磁共振波谱。影像学表现为多个占位性病变，T1加权成像低信号，T2加权成像均匀高信号，增强扫描明显增强。DWI显示扩散受限，PWI显示低灌注，光谱显示胆碱峰升高，N-乙酰天冬氨酸降低。激素休克治疗后，患者的病情明显好转。结论：本病例突出了PCNSL的独特影像学特征及其在准确诊断和治疗中的重要性。

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World journal of radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

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