{"title":"Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report.","authors":"Li-Hong Liu, Han-Wen Zhang, Hong-Bo Zhang, Xiao-Lei Liu, Hua-Zhen Deng, Fan Lin, Biao Huang","doi":"10.4329/wjr.v15.i9.274","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics.</p><p><strong>Case summary: </strong>Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy.</p><p><strong>Conclusion: </strong>This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":"15 9","pages":"274-280"},"PeriodicalIF":1.4000,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/8f/WJR-15-274.PMC10563853.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World journal of radiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4329/wjr.v15.i9.274","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics.
Case summary: Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy.
Conclusion: This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management.