Clinical impact of capsule endoscopy on patients with suspected small bowel bleeding: Experience at a highly specialized hospital in Colombia

C.J. Vargas-Potes , I.L. Zapata-Vásquez , N.E. Rojas-Rojas , C.A. Rojas-Rodríguez
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Abstract

Introduction and aims

Capsule endoscopy is part of the diagnostic approach to patients with suspected small bowel bleeding and data on its clinical impact are still limited in developing countries. The primary aim of the present study was to determine its impact on subsequent diagnostic and therapeutic decisions.

Material and methods

A retrospective study was conducted that included all the patients that underwent capsule endoscopy with the PillCam™ SB 3 Capsule system due to suspected small bowel bleeding treated at the Hospital Universitario Fundación Valle del Lili between January 2011 and December 2020.

Results

A total of 158 patients met the inclusion criteria. Mean patient age was 63 years (interquartile range [IQR], 52-74), 53.6% of the patients were women, and high blood pressure was the most frequent comorbidity (43.7%). The main indication was overt bleeding (58.2%). Of all the capsule endoscopies carried out, 63.9% showed lesions that were potentially responsible for bleeding. Medical or surgical treatment was indicated in 63.3% of the case total. Rebleeding at 6 months occurred in 15 patients and there were 2 deaths due to gastrointestinal bleeding at 6 months.

Conclusions

Capsule endoscopy has a high impact on patients with suspected small bowel bleeding, with respect to clinical decision-making, as well as rebleeding, hospitalization, and mortality outcomes. The positivity rate of lesions potentially responsible for bleeding was similar to that reported in developed countries.

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胶囊内镜对疑似小肠出血患者的临床影响:哥伦比亚一家高度专业化医院的经验。
引言和目的:胶囊内窥镜检查是疑似小肠出血患者诊断方法的一部分,关于其临床影响的数据在发展中国家仍然有限。本研究的主要目的是确定其对后续诊断和治疗决策的影响。材料和方法:进行了一项回顾性研究,包括所有使用PillCam进行胶囊内窥镜检查的患者™ 2011年1月至2020年12月,在瓦利大学基金会医院治疗疑似小肠出血的SB 3胶囊系统。结果:共有158名患者符合入选标准。平均患者年龄为63岁(四分位间距[IQR],52-74),53.6%的患者为女性,高血压是最常见的合并症(43.7%)。主要指征是明显出血(58.2%)。在所有进行的胶囊内镜检查中,63.9%的患者显示可能导致出血的病变。63.3%的病例需要内科或外科治疗。15例患者在6个月时再次出血,其中2例因6个月胃肠道出血死亡。结论:胶囊内镜对疑似小肠出血患者的临床决策、再出血、住院治疗和死亡率有很大影响。可能导致出血的病变的阳性率与发达国家的报告相似。
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