On the Use of Artificial Intelligence for Dosimetry of Radiopharmaceutical Therapies.

Nuklearmedizin. Nuclear medicine Pub Date : 2023-12-01 Epub Date: 2023-10-12 DOI:10.1055/a-2179-6872
Julia Franziska Brosch-Lenz, Astrid Delker, Fabian Schmidt, Johannes Tran-Gia
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Abstract

Routine clinical dosimetry along with radiopharmaceutical therapies is key for future treatment personalization. However, dosimetry is considered complex and time-consuming with various challenges amongst the required steps within the dosimetry workflow. The general workflow for image-based dosimetry consists of quantitative imaging, the segmentation of organs and tumors, fitting of the time-activity-curves, and the conversion to absorbed dose. This work reviews the potential and advantages of the use of artificial intelligence to improve speed and accuracy of every single step of the dosimetry workflow.

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人工智能在放射药物治疗剂量测定中的应用。
常规临床剂量测定和放射药物治疗是未来个性化治疗的关键。然而,剂量测定被认为是复杂和耗时的,在剂量测定工作流程中所需的步骤中存在各种挑战。基于图像的剂量测定的一般工作流程包括定量成像、器官和肿瘤的分割、时间活动曲线的拟合以及转换为吸收剂量。这项工作回顾了使用人工智能来提高剂量测定工作流程每一步的速度和准确性的潜力和优势。
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