Adherence to antimalarial drug policy among doctors in Delta State, Nigeria: implications for malaria control.

Irikefe P Obiebi
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引用次数: 10

Abstract

Background: Malaria is a public health problem compounded with a widespread emergence of drug-resistant Plasmodium falciparum which necessitated the formulation of a new antimalarial drug policy (AMP).

Objective: This study was designed to assess adherence to the policy among physicians in health facilities in Delta state, Nigeria.

Design: Cross-sectional, analytic study. Data were collected with a semi-structured questionnaire.

Setting: Two secondary and one tertiary health facilities in Delta State, Nigeria.

Participants: Physicians selected with a simple random technique from the facilities.

Main outcome measures: Prescribing pattern of antimalarial drugs and adherence to WHO treatment guideline among doctors.

Results: Majority (90.8%) of respondents believed the antimalarial policy (AMP) should be strictly adhered to, although three-fifth (61.0%) of them rated its performance as poor. The level of adherence to the national antimalarial drug policy was high (78.5%) as most doctors prescribed Arthemeter-Lumefantrine, AL for uncomplicated malaria however barely two-fifth (35.4%) adhered to prescribing injectable Artesunate for complicated malaria. AL, (71.9%) was the most prescribed antimalarial drug for uncomplicated malaria The most prescribed antimalarial drugs for complicated malaria was artesunate (40.0%) followed by quinine (27.6%) and artemether (26.7%); although, chloroquine was also prescribed.

Conclusion: The level of adherence to AMP among doctors was sub-optimal. Continuous education of doctors on the new AMP is needed to achieve malarial control.

Funding: No funding was received for this study.

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尼日利亚三角洲州医生对抗疟药物政策的遵守情况:对疟疾控制的影响。
背景:疟疾是一个公共卫生问题,加上抗药性恶性疟原虫的广泛出现,需要制定新的抗疟药物政策。目的:本研究旨在评估尼日利亚三角洲州卫生机构医生对该政策的遵守情况。设计:横截面分析研究。采用半结构化问卷收集数据。环境:尼日利亚三角洲州的两个二级和一个三级卫生设施。参与者:通过简单的随机技术从这些设施中选出的医生。主要观察指标:医生抗疟药物的处方模式和对世界卫生组织治疗指南的遵守情况。结果:大多数(90.8%)受访者认为应严格遵守抗疟政策,尽管五分之三(61.0%)的受访者认为其表现不佳。对国家抗疟药物政策的遵守率很高(78.5%),因为大多数医生为无并发症的疟疾开了Arthemeter Lumefantrine,AL,但只有五分之二(35.4%)的医生坚持为复杂的疟疾开注射用青蒿琥酯。AL(71.9%)是治疗非复杂疟疾的最常用抗疟药物。治疗复杂疟疾的最多处方抗疟药物是青蒿琥酯(40.0%),其次是奎宁(27.6%)和蒿甲醚(26.7%);尽管如此,氯喹也被开了处方。结论:医生对AMP的依从性处于次优水平。需要对医生进行关于新AMP的持续教育,以实现疟疾控制。资助:本研究未收到任何资助。
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