Relationship between axial length and spherical equivalent refraction in Chinese children

Advances in ophthalmology practice and research Pub Date : 2021-12-01 DOI:10.1016/j.aopr.2021.100010

Shuying Chen, Xin Liu, Xiaotong Sha, Xiaoxia Yang, Xiaoning Yu

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引用次数: 1

Abstract

Purpose

To evaluate the relationship between axial length (AL) and spherical equivalent refraction (SER) in Chinese children.

Methods

This hospital-based cross-sectional study included 1208 eyes (from 617 Chinese boys and 591 Chinese girls), ranging between 2 and 12 years. All subjects were divided into subgroups according to the spherical equivalent refraction (SER) (hyperopia, emmetropia, and myopia) and age (2–6 years, 7–9 years, and 10–12 years). Comparisons were made between age, sex, and SER groups. Multiple linear regression analysis was used to evaluate the correlation of AL and SER for all groups.

Results

The mean AL and SER were significantly different among the three age groups: 2–6 years group (AL: 22.24 ± 1.59 mm; SER: 0.73 ± 2.67 D); 7–9 years group (AL: 23.49 ± 1.10 mm; SE: -0.68 ± 1.97 D) and 10–12 years group (AL: 24.33 ± 1.02 mm; SER: -1.72 ± 1.86 D). Boys showed longer AL compared with the girls (23.66 ± 1.51 mm vs 23.05 ± 1.32 mm). However, as for SER, the girls (−0.70 ± 2.17 D) showed smaller SER (more myopia) compared with the boys (−0.4 ± 2.48 D). After adjusting for age and sex, the SER tended to decrease (became more myopic) 1.23 D (95% CI: 1.15–1.30D) with a 1 mm increase of AL. Among the different SER groups, the SER tended to become more myopic per mm of AL by 1.09 D (95% CI: 0.97–1.21D) for the myopia group, 1.38 D (95% CI: 1.23–1.54 D) for the hyperopia group, and 0.05 D (95% CI: 0.02–0.08 D) for the emmetropic group. In addition, an increase of 1 mm elongation of AL showed a decrease of SER by 1.05 D (95% CI: 0.90–1.20 D) among 2 – 6-year-olds, by 1.40 D (95% CI: 1.30–1.51 D) among 7 – 9-year-olds, and by 1.37 D (95% CI: 1.21–1.52 D) among 10–12-year-olds. As for sexual differences, the girls 1.68 D, (95% CI: 1.57–1.79 D) showed a more significant myopic shift of SER with a 1 mm increase of AL compared with the boys (0.94 D, 95% CI: 0.84–1.04 D).

Conclusions

Our results indicated a strong linear relationship between SER and AL and an early-rising trend of myopia in Chinese children.

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中国儿童眼轴长与球面等效折射的关系

目的探讨中国儿童视轴长(AL)与球面等效折射(SER)的关系。方法以医院为基础的横断面研究包括1208只眼睛(来自617名中国男孩和591名中国女孩)，年龄在2至12岁之间。根据球体等效屈光度(SER)(远视、远视和近视眼)和年龄(2-6岁、7-9岁和10-12岁)将所有受试者分为亚组。在年龄、性别和SER组之间进行比较。采用多元线性回归分析评价各组AL与SER的相关性。结果3个年龄组AL、SER均值差异有统计学意义:2 ~ 6岁组(AL: 22.24±1.59 mm;Ser: 0.73±2.67 d);7 ~ 9岁组(AL: 23.49±1.10 mm;SE: -0.68±1.97 D)和10 - 12年组(艾尔:24.33±1.02毫米;SER: -1.72±1.86 D)，男孩AL较女孩长(23.66±1.51 mm vs 23.05±1.32 mm)。然而,至于爵士,女孩(−0.70±2.17 D)显示小爵士(近视)与男孩相比(−0.4±2.48 D)。在调整了年龄和性别,SER倾向于减少(变得近视)1.23 D(95%置信区间:1.15—-1.30 D)增加了1毫米。在不同的SER组,每毫米SER倾向于更加近视的1.09 D(95%置信区间:0.97—-1.21 D)近视组,1.38 D(95%置信区间:1.23—-1.54 D)远视集团和0.05 D(95%置信区间CI:0.02 ~ 0.08 D)。此外，AL每增加1 mm, 2 ~ 6岁儿童SER降低1.05 D (95% CI: 0.90 ~ 1.20 D)， 7 ~ 9岁儿童SER降低1.40 D (95% CI: 1.30 ~ 1.51 D)， 10 ~ 12岁儿童SER降低1.37 D (95% CI: 1.21 ~ 1.52 D)。性别差异方面，女孩(1.68 D, 95% CI: 1.57 ~ 1.79 D)较男孩(0.94 D, 95% CI: 0.84 ~ 1.04 D)表现出更显著的近视SER偏移，AL升高1 mm。结论SER与AL之间存在较强的线性关系，中国儿童近视呈早期上升趋势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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