Hospital Readmission in Patients With Diabetic Foot Ulcers: Prevalence, Causes, and Outcomes.

Marco Meloni, Aikaterini Andreadi, Valeria Ruotolo, Maria Romano, Ermanno Bellizzi, Laura Giurato, Alfonso Bellia, Luigi Uccioli, Davide Lauro
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Abstract

The aim of the current study was to evaluate the rate of readmission in patients affected by diabetes and foot ulcers (DFUs), and causes and outcomes of patients requiring a new hospitalization. The current study is a retrospective observational study including patients who have required hospitalization since January 2019 to September 2022 due to a DFU. Once patients were discharged, they were regularly followed as outpatients. Within 6 months of follow-up, the rate of hospital readmission for a diabetic foot problem was recorded. According to the readmission or not, patients were divided into 2 groups, readmitted and not readmitted patients, respectively. Hence, all patients were followed for 6 months more and outcomes of the 2 groups were analyzed and compared. Overall, 310 patients were included. The mean age was 68  ±  12 years, the majority of patients reported type 2 diabetes (>90%), and the mean diabetes duration was approximately 20 years. Sixty-eight (21.9%) patients were readmitted. The main reason for hospital readmission was the presence of critical limb ischemia (CLI) in the contralateral limb (6.1%), the recurrence of CLI in the previous treated limb (4.5%), and the onset of new infected DFU in the contralateral foot (4.5%). Readmitted patients reported lower rate of healing (51.5% vs 89.2%, P < .0001) and higher rate of major amputation (10.3% vs 4.5%, P  =  .2) in comparison to not readmitted patients. Critical limb ischemia resulted in the only independent predictor of hospital readmission. Hospital readmission is a frequent issue among patients with DFUs, and readmitted patients showed a lower chance of wound healing. Critical limb ischemia resulted in the main cause of new hospitalization.

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糖尿病足溃疡患者的医院再诊断:患病率、原因和结果。
本研究的目的是评估糖尿病和足部溃疡(DFU)患者的再入院率,以及需要新住院治疗的患者的原因和结果。目前的研究是一项回顾性观察性研究,包括自2019年1月至2022年9月因DFU需要住院治疗的患者。一旦病人出院,他们就作为门诊病人定期接受随访。在随访的6个月内,记录糖尿病足问题的再次入院率。根据是否再次入院,将患者分为两组,分别为再次入院和未再次入院患者。因此,所有患者都接受了6个月以上的随访,并对两组的结果进行了分析和比较。总共纳入310名患者。平均年龄68岁  ±  12年后,大多数患者报告2型糖尿病(>90%),平均糖尿病持续时间约为20年。68名(21.9%)患者再次入院。再次入院的主要原因是对侧肢体存在严重肢体缺血(CLI)(6.1%),先前治疗的肢体出现严重肢体缺血复发(4.5%),对侧足部出现新感染的DFU(4.5%) P  =  .2) 与未再次入院的患者相比。严重的肢体缺血是再次入院的唯一独立预测因素。在DFU患者中,再次入院是一个常见的问题,再次入院的患者伤口愈合的几率较低。严重的肢体缺血是新住院的主要原因。
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